Efeito do concentrado de plaquetas xenólogo na cicatrização da córnea em coelhos
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Data
2010
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Resumo
Corneal injuries are common in veterinary
ophthalmology and can sometimes cause loss of visual
capacity. Eighteen adult rabbits were submitted to superficial
keratectomy procedures and then separated into three groups for
macroscopic and histological evaluation on the 7th, 15th and
30th of the postoperative period. The corneas of the left eye
received topical administration to bovine concentrated plasma
rich in platelets (PRP) as well as topical antibiotic tobramycin
while the right eye received only topical antibiotic tobramycin.
It was noted that in the eyes treated with topical application
of the antibiotic, the corneal lesion was covered by a thin epithelium
and there was an intense disorganization of substancia
propria with areas of necrosis. In the eyes medicated with PRP
reepithelialization was apparently normal, with smaller areas of
acanthosis and substancia propria had thin collagen fibers. We
concluded that the bovine concentrated plasma rich in platelets stimulates and organizes the process of repairing of corneas
injuries in rabbits with reduction of necrosis areas and corneal
opacity.
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Palavras-chave
Concentrado de plasma de bovino rico em plaquetas, Córnea, Cicatrização, Coelhos, Bovine concentrated plasma riche in platelets, Cornea, Healing, Rabbits
Citação
EURIDES, Duvaldo; MANTOVANI, Matheus M.; MENEZES, Gabriel F.; SILVA, Luiz A. F. da; SOUZA, Luiz A.; OLIVEIRA, Benito J. N. A.; BAUNGARTEN, Letícia B.; DELBEN, Ana F. P. A. Efeito do concentrado de plaquetas xenólogo na cicatrização da córnea em coelhos. Revista Portuguesa de Ciências Veterinárias, Lisboa, v. 105, n. 573/576, p. 39-43, 2010.