Perfil de resistência dos Staphylococcus aureus isolados de sangue e cateter

Resumo

Staphylococcus aureus bacteria are responsible for causing various diseases, from localized skin infections to severe systemic infections such as bloodstream infections (BSI). The Staphylococcus aureus strains were isolated from clinical specimens of ENCICLOPÉDIA BIOSFERA, Centro Científico Conhecer - Goiânia, v.10, n.19; p. 201389 4 blood and catheter tips, and sub cultured on nutrient Agar and subjected to antimicrobial susceptibility testing. Of the total 602 samples, 268 strains of Staphylococcus aureus were identified. Of these were isolated 233 (87%) MRSA strains and 35 (13%) MSSA strains. When analyzing clinical specimens MRSA was more isolated in the catheter tip (52.2%) compared to blood (47.7%), this being the most frequent pathogen in the ICU (36%), medical (30%), surgical center (18%), trauma (3.8%), intermediate clinic (3.8%), and nursing (2.1%) followed by other units (2.5%). MRSA showed statistically significant differences for resistance to ciprofloxacin, trimethoprim-sulfamethoxazole, rifampin, clindamycin, erythromycin and gentamicin, being the resistance factor favorable to use more than three antimicrobials. The strategy to revert this situation includes the reduction of indiscriminate use of antibiotics and encouraging the development of effective protocols for the prevention and control of Healthcare-Associated Infections (HAIs) through knowledge of the resistance of MRSA to the antimicrobial profile. KEYWORDS: MRSA, Blood, Catheter tip, Multi-resistance.

Descrição

Palavras-chave

Multirressistência, MRSA, Sangue, Ponta de Cateter, Blood, Catheter tip, Multi-resistance

Citação

PENA, D. R. ; RODRIGUES, G. ; KOBAYASCHI, C. A.; VIEIRA, J. D. G.; SADOYAMA, G. Perfil de resistência dos staphylococcus aureus isolados de sangue e cateter. Enciclopédia Biosfera, Goiânia, v. 10, n. 19, p. 388-396, 2014.