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Tipo do documento: Artigo
Título: Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies
Autor: Gomes, Yara de Miranda
Lorena, Virgínia Maria Barros de
Ostermayer, Alejandro Luquetti
Abstract: In the acute phase and in the chronic forms of Chagas disease, the etiological diagnosis may be performed by detection of the parasite using direct or indirect parasitological methods and by the presence of antibodies in the serum by way of serological tests. Several techniques are easily available, ranging from the simplest wet smear preparation to immuno-enzymatic assays with recombinant antigens that will meet most diagnostic needs. Other tests under evaluation include a molecular test using polymerase chain reaction, which has shown promising results and may be used as a confirmatory test both in the acute and chronic phases of the disease. Better rapid tests are needed for diagnosis, some of which are already under evaluation. Additionally, there is a need for tools that can identify patients cured shortly after specific treatment. Other needs include a marker for prognosis and early diagnosis of congenital transmission.
Palavras-chave: Chagas disease
Trypanosoma cruzi
Etiological diagnosis
País: Brasil
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: GOMES, Yara M.; LORENA, Virgínia M. B.; LUQUETTI, Alejandro O. Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies? Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 104, supl. I, p. 797-800, 2009.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S0074-02762009000900017
Identificador do documento: 10.1590/S0074-02762009000900017
Data de publicação: 2009
Aparece nas coleções:FM - Artigos publicados em periódicos

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