Estudo da atividade citotóxica do extrato bruto etanólico de Psychotria prunifolia (Rubiaceae) em células tumorais e normais in vitro
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Data
2011
Título da Revista
ISSN da Revista
Título de Volume
Editor
Vera Lúcia Gomes Klein
Resumo
The use of medicinal plants has become a widely accepted therapeutic alternative by the
population and it has been also growing in the medical community, provided that their biological activities,
efficacy, and safety have been scientifically investigated and proved. Therefore we investigated the
cytotoxic potential of the crude ethanolic extract of Psychotria prunifolia in tumor and normal cells, used
as the control for tumor cells. To do this, we used two independent tests: the MTT and trypan blue. The
results suggest that this plant presents cytotoxic activity in tumor cells, although this activity could also
be observed in normal cells. Thus, it is necessary to perform more detailed studies, since the plant has
proved promising with regard to antitumor activity.
Descrição
v. 8, n. 1, p. 15-23, 2011.
Palavras-chave
Atividade citotóxica, Azul de tripano, MTT, Psychotria prunifolia
Citação
PIRES, Wanessa Carvalho; MELLO, Francyelli Mariana dos Santos; BATISTA, Mariana Pedrosa; PEREIRA, Flávia de Castro; LIMA, Aliny Pereira; VILANOVA-COSTA, Cesar Augusto Sam Tiago; KATO, Lucilia; SILVEIRA-LACERDA, Elisângela de Paula. Estudo da atividade citotóxica do extrato bruto etanólico de Psychotria prunifolia (Rubiaceae) em células tumorais e normais in vitro. Revista de Biologia Neotropical, v. 8, n. 1, p. 15-23, 2011. Disponível em:<http://www.revistas.ufg.br/index.php/RBN/article/view/8117/10050>.