Vacinação contra Haemophilus influenzae tipo b: proteção a longo prazo
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Data
2006
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Resumo
Objective: To identify evidence of the impact of Haemophilus
influenzae type b (Hib) conjugate vaccine on the epidemiology of
invasive Hib disease.
Sources of data: This review was based on a search of MEDLINE,
LILACS, technical reports, national and international guidelines
(publications from 1991 to 2005). The keywords Haemophilus
influenzae type b, immunization, impact and effectiveness, alone or
in combination, were used to retrieve the articles. Studies published
before 1991 and cited in the references of the studies reviewed were
analyzed for useful information.
Summary of the findings: Introduction of the Hib conjugate
vaccine produced great decline in the incidence of invasive Hib
disease in childhood in countries where this vaccine was introduced
into the routine immunization schedule. Nevertheless, the resurgence
of invasive Hib disease in some regions has challenged several
researchers to identify the reasons for this epidemiological pattern,
as well as the measures to be implemented in order to avoid such a
phenomenon.
Conclusions: The use of Hib conjugate vaccine on a population
scale has been greatly effective; nonetheless, changes in the
vaccination scheme seem to be necessary to keep invasive Hib
disease under control.
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Pneumonia, Haemophilus influenzae tipo B, Imunização, Vacina, Meningite, Pneumonia, Haemophilus influenzae type B, Immunization, Vaccine, Meningitis
Citação
NASCIMENTO-CARVALHO, Cristiana M.; ANDRADE, Ana Lúcia S. Sgambatti de. Vacinação contra Haemophilus influenzae tipo b: proteção a longo prazo. Jornal de Pediatria, Porto Alegre, v. 82, n. 3, 2006.