Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15227
Tipo do documento: Artigo
Título: Cytotoxicity of glass ionomer cements containing silver nanoparticles
Autor: Siqueira, Patrícia Correia
Magalhães, Ana Paula Rodrigues
Pires, Wanessa Carvalho
Pereira, Flávia Castro
Lacerda, Elisângela Paula Silveira
Carrião, Marcus Santos
Bakuzis, Andris Figueiroa
Costa, Carlos Alberto Souza
Lopes, Lawrence Gonzaga
Estrela, Carlos
Abstract: Background: Some studies have investigated the possibility of incorporating silver nanoparticles (NAg) into dental materials to improve their antibacterial properties. However, the potential toxic effect of this material on pulp cells should be investigated in order to avoid additional damage to the pulp tissue. This study evaluated the cytotoxicity of conventional and resin-modified glass ionomer cements (GIC) with and without addition of NAg. Material and Methods: NAg were added to the materials at two different concentrations by weight: 0.1% and 0.2%. Specimens with standardized dimensions were prepared, immersed in 400 μL of culture medium and incubated at 37°C and 5% CO2 for 48 h to prepare GIC liquid extracts, which were then incubated in contact with cells for 48 h. Culture medium and 0.78% NAg solution were used as negative and positive controls, respectively. Cell viability was determined by MTT and Trypan Blue assays. ANOVA and the Tukey test (α=0.05) were used for statistical analyses. Results: Both tests revealed a significant decrease in cell viability in all groups of resin modified cements (p˂0.001). There were no statistically significant differences between groups with and without NAg (p˃0.05). The differences in cell viability between any group of conventional GIC and the negative control were not statistically significant (p>0.05). Conclusions: NAg did not affect the cytotoxicity of the GIC under evaluation.
Palavras-chave: Glass ionomer cements
Totoxicity
Cell culture techniques
Nanotechnology
Metal nanoparticles
País: Espanha
Unidade acadêmica: Instituto de Física - IF (RG)
Citação: SIQUEIRA, Patrícia Correia; MAGALHÃES, Ana Paula Rodrigues; PIRES, Wanessa Carvalho; PEREIRA, Flávia Castro; LACERDA, Elisângela Paula Silveira; CARRIÃO, Marcus Santos; BAKUZIS, Andris Figueiroa; COSTA, Carlos Alberto Souza; LOPES, Lawrence Gonzaga; ESTRELA, Carlos. Cytotoxicity of glass ionomer cements containing silver nanoparticles. Journal of Clinical and Experimental Dentistry, Valência, v. 7, n. 5, p. 622-627, 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.4317/jced.52566
Identificador do documento: 10.4317/jced.52566
URI: http://repositorio.bc.ufg.br/handle/ri/15227
Data de publicação: 2015
Aparece nas coleções:IF - Artigos publicados em periódicos

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