Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15323
Tipo do documento: Artigo
Título: Seroprevalence of Triatoma virus (Dicistroviridae: Cripaviridae) antibodies in Chagas disease patients
Autor: Querido, Jailson F. Brito
Echeverría, María Gabriela
Marti, Gerardo Aníbal
Costa, Rita Medina
Susevich, María Laura
Rabinovich, Jorge Eduardo
Copa, Aydee
Villarroel, Nair Alaide Montaño
Garcia, Lineth
Cordova, Marisol
Torrico, Faustino
Sánchez Eugenia, Rubén
Sánchez Magraner, Lissete
Muñiz Trabudua, Xabier
López Marijuan, Ibai
Rozas Dennis, Gabriela Susana
Diosque, Patricio
Castro, Ana Maria de
Robello, Carlos
Rodríguez, Julio S.
Altcheh, Jaime
Salazar Schettino, Paz Maria
Bucio Torres, Martha Irene
Espinoza, Bertha
Guérin Aguilar, Diego M.
Silva, Marcelo de Sousa da
Abstract: Background: Chagas disease is caused by Trypanosoma cruzi, and humans acquire the parasite by exposure to contaminated feces from hematophagous insect vectors known as triatomines. Triatoma virus (TrV) is the sole viral pathogen of triatomines, and is transmitted among insects through the fecal-oral route and, as it happens with T. cruzi, the infected insects release the virus when defecating during or after blood uptake. Methods: In this work, we analysed the occurrence of anti-TrV antibodies in human sera from Chagas disease endemic and non-endemic countries, and developed a mathematical model to estimate the transmission probability of TrV from insects to man, which ranged between 0.00053 and 0.0015. Results: Our results confirm that people with Chagas disease living in Bolivia, Argentina and Mexico have been exposed to TrV, and that TrV is unable to replicate in human hosts. Conclusions: We presented the first experimental evidence of antibodies against TrV structural proteins in human sera.
Palavras-chave: Triatoma virus,
Passive viral exposure
Dicistroviridae
Biological control
Trypanosoma cruzi
Mathematical model
Triatomines
Chagas disease
País: Gra-bretanha
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: QUERIDO, Jailson F. B. et al. Seroprevalence of Triatoma virus (Dicistroviridae: Cripaviridae) antibodies in Chagas disease patients. Parasites & Vectors, London, v. 8, p. 1-9, 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1186/s13071-015-0632-9
Identificador do documento: 10.1186/s13071-015-0632-9
URI: http://repositorio.bc.ufg.br/handle/ri/15323
Data de publicação: 2015
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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