Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15324
Tipo do documento: Artigo
Título: Anatomopathological study in Balb/C mice brains experimentally infected with Toxoplasma gondii
Autor: Silva, Marcos Gontijo da
Lino Junior, Ruy de Souza
Costa, Tatiane Luiza da
Soares, Joanna Darc Aparecida Herzog
Amaral, Waldemar Naves do
Avelino, Mariza Martins
Castro, Ana Maria de
Abstract: Toxoplasmosis is one of the most important diseases of the nervous central system, leading to severe symptoms and, many times, irreversible sequelae. This work demonstrated the main anatomopathological lesions caused by Toxoplasma gondii in brains from experimentally infected BALB/c mice. We analyzed 51 cases of mice that developed toxoplasmosis after experimental infection by intraperitoneal inoculation of blood, amniotic liquid and cerebrospinal fluid from fetuses, newly born children and pregnant women with clinical and laboratory signals of toxoplasmosis. In all experiments where we detected the parasite in mice we also detected pathological lesions in the animal brains with great polymorphism between experiments. Edema was the most found lesion in all cases. Besides, it was possible to demonstrate the inflammatory process in 82.4% of cases and necrosis in 64.7% of cases, in agreement with the literature that describes severe neurological damage in its hosts.
Palavras-chave: Toxoplasmosis
Mice brains
Experimental histopathology
País: Brasil
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: SILVA, Marcos Gontijo da; LINO JUNIOR, Ruy de Souza; COSTA, Tatiane Luiza da; SOARES, Joanna D'arc Herzog; AMARAL, Waldemar Naves do; AVELINO, Mariza Martins; CASTRO, Ana Maria de. Anatomopathological study in Balb/C mice brains experimentally infected with Toxoplasma gondii. Brazilian Journal of Infectious Diseases, Salvador, v. 12, n. 1, p. 52-56, Feb. 2008.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S1413-86702008000100012
Identificador do documento: 10.1590/S1413-86702008000100012
URI: http://repositorio.bc.ufg.br/handle/ri/15324
Data de publicação: 2008
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

Arquivos associados a este item:
Arquivo Descrição TamanhoFormato 
Artigo - Marcos Gontijo da Silva - 2008.pdf156,21 kBAdobe PDFThumbnail
Baixar/Abrir


Este item está licenciada sob uma Licença Creative Commons Creative Commons