Toxoplasma gondii primary infection in pregnant women in Goiânia: a seroconversion study
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Data
2009-12
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Resumo
The purpose of this study was to test toxoplasmosis seroconversion in pregnant women in Goiânia-GO, a city in the Midwestern
Region of Brazil. A prospective observational study of pregnant women vulnerable to Toxoplasma gondii was carried out using
Indirect Immunofluorescent Antibody Test (IFAT) for serological screening and laboratorial surveillance of seroconversion. The
immunoenzyme test (ELISA) was performed to confirm acute toxoplasmosis. The risk estimate used limits of reliability at 95%
and the results were validated by 2 and RR tests. Acute infection found in the pregnant women participating in this study was
8.6% (45/522). Living in close contact with host animals and vehicles of oocyst transmission constituted statistical risks for
pregnant women to acquire acute toxoplasmosis. This research revealed seroconversion (8.6%), pointing to the need of primary
and secondary prevention for all pregnant women at risk (seronegative). This study originated a program for the protection of
pregnant women in the state of Goiás.
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Palavras-chave
Toxoplasma gondii, Seroconversion, Pregnant women, Gestantes, Soroconversão
Citação
AVELINO, Mariza M. et. al. Toxoplasma gondii primary infection in pregnant women in Goiânia: a seroconversion study. Revista Ciências Médicas e Biológicas, Salvador, v. 8, p. 325-333, Sept./Dec. 2009.