Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15421
Tipo do documento: Artigo
Título: Human bocavirus 1 and 3 infection in children with acute gastroenteritis in Brazil
Autor: Sousa, Teresinha Teixeira de
Souza, Menira Borges de Lima Dias e
Fiaccadori, Fabíola Souza
Borges, Ana Maria Tavares
Costa, Paulo Sérgio Sucasas da
Cardoso, Divina das Dôres de Paula
Abstract: To determine the positivity rate of human bocavirus (HBoV) 1 and 3 among children who presented with acute gastroenteritis symptoms during the period of 1994-2004 in the Central-West Region of Brazil, 762 faecal samples were tested using polymerase chain reaction (PCR) for the detection of HBoV DNA. Primers for a segment of the non-structural viral protein 1 (NS1) gene of HBoV-1 and HBoV-3 were used. Twelve HBoV-positive samples were further characterised via genomic sequencing and phylogenetic analysis. Of the samples tested, 5.8% (n = 44) were positive for HBoV-1 or HBoV-3 and co-infection was observed in 14 (31.8%) of the 44 HBoV-positive samples. Nine of the 14 samples were also positive for Rotavirus A and five were positive for Aichi virus. The genomic sequencing of the NS1 partial sequence of 12 HBoV-samples showed that 11 samples were characterised as HBoV-1 and that one was characterised as HBoV-3. The phylogenetic analysis showed that the HBoV-1 samples had a high sequence homology to others previously identified in China, Sweden and Brazil. This is the first study conducted in the Cen- tral-West Region of Brazil to detect HBoV-1 and HBoV-3 in faecal samples from children with acute gastroenteritis. Further studies are required to define the role of HBoVs as aetiological agents of gastroenteritis.
Palavras-chave: Human bocavirus
Brazil
Acute gastroenteritis
Molecular characterisation
País: Brasil
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: SOUSA, Teresinha Teixeira de; SOUZA, Menira; FIACCADORI, Fabíola Souza; BORGES, Ana Maria Tavares; COSTA, Paulo Sucasas da; CARDOSO, Divina das Dôres de Paula. Human bocavirus 1 and 3 infection in children with acute gastroenteritis in Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 107, n. 6, p. 800-804, Sept. 2012.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S0074-02762012000600015
Identificador do documento: 10.1590/S0074-02762012000600015
URI: http://repositorio.bc.ufg.br/handle/ri/15421
Data de publicação: Set-2012
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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