Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15481
Tipo do documento: Artigo
Título: A comparative study of the organic content of the hemolymph of Schistosoma mansoni-resistant and susceptible strains of Biomphalaria glabrata
Autor: Bezerra, José Clecildo Barreto
Becker, Wilhelm
Zelck, Ulrike E.
Abstract: The freshwater snail Biomphalaria glabrata is an intermediate host of the trematode Schistosoma mansoni. However, some strains of B. glabrata are resistant to successful infection by S. mansoni larvae. The present work examines the profile of organic acids present in S. mansoni-resistant and -susceptible strains of B. glabrata, in order to determine whether the type of organic acid present is related to susceptibility. The organic acids were extracted from the hemolymph of two susceptible B. glabrata strains (PR, Puerto Rico and Ba, Jacobina-Bahia from Brazil), and from the resistant strains 13-16-R1 and 10R2, using solid phase extraction procedures followed by high performance liquid chromatography. The organic acids obtained were analyzed and identified by comparison with known standards. Pyruvate, lactate, succinate, malate, fumarate, acetate, propionate, ß-hydroxybutyrate and acetoacetate were detected in all hemolymph samples. Under standard conditions, the concentration of each of these substances varied among the strains tested and appeared to be specific for each strain. An interesting variation was the low concentration of pyruvate in the hemolymph of PR-snails. Only the concentration of fumarate was consistently different (p≤ 0.05) between resistant and susceptible strains.
Palavras-chave: Biomphalaria glabrata
Susceptibility
Host-parasite interaction
Schistosoma mansoni
Organic acids
Resistance
País: Brasil
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: BEZERRA, José Clecildo Barreto; BECKER, Wilhelm; ZELCK, Ulrike E. A comparative study of the organic content of the hemolymph of Schistosoma mansoni-resistant and susceptible strains of biomphalaria glabrata. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 92, n. 3, p. 421-425, May/Jun. 1997.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S0074-02761997000300021
Identificador do documento: 10.1590/S0074-02761997000300021
URI: http://repositorio.bc.ufg.br/handle/ri/15481
Data de publicação: Jun-1997
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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