Epidemiology of the viral hepatitis B and C in female prisoners of metropolitan regional prison complex in the state of Goiás, central Brazil
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2013-02
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Introduction: Little information regarding hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among Brazilian female
prisoners exists. This study investigated the prevalence and risk factors associated with HBV and HCV infections and identified
viral genotypes among female prisoners in Goiás, Central Brazil. Methods: Women incarcerated in the largest prison in the State
of Goiás were invited to participate in the study. All female prisoners were interviewed and tested for the detection of hepatitis B
surface antigen (HBsAg), antibodies against HBsAg (anti-HBs), against hepatitis B core antigen (anti-HBc), and antibody against
HCV (anti-HCV) by ELISA. HBsAg and anti-HCV positive samples were tested for HBV DNA and HCV RNA and genotyped,
respectively. Results: Participants (n=148; 98.6%) completed the study with an overall HBV prevalence of 18.9%. Age >30 years,
a low education level, sex with a sexually transmitted diseases carrier, and a male sexual partner serving in the same penitentiary
were associated with HBV infections. Only 24% of the women were anti-HBs positive suggesting previous HBV vaccination. Nine
female prisoners (6.1%) were anti-HCV positive. Age >40 years, injecting drug use and length of incarceration were statistically
associated with anti-HCV antibodies. Five samples were HCV RNA positive and classified as genotypes 1 (subtypes 1a; n=3 and
1b; n=1) and 3 (subtype 3a; n=1). The HBsAg-reactive sample was HBV DNA positive and genotype A. Conclusions: These
findings highlight the necessity of public policies to control hepatitis B and C infections and emphasize the importance of hepatitis
B vaccination in prison environments.
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Hepatitis B, Associated factors, Hepatitis C, Female inmates, Prevalence, Genotypes
Citação
BARROS, Láiza Alencar Santos; PESSONI, Grécia Carolina; TELES, Sheila Araújo; SOUZA, Sandra Maria Brunini de; MATOS, Marcos André de; MARTINS, Regina Maria Bringel; DEL-RIOS, Nativa Helena Alves; MATOS, Márcia Alves Dias de; CARNEIRO, Megmar Aparecida dos Santos. Epidemiology of the viral hepatitis B and C in female prisoners of metropolitan regional prison complex in the state of Goiás, central Brazil. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 46, n. 1, p. 24-29, Jan./Feb. 2013.