Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15522
Tipo do documento: Artigo
Título: Y-STR haplotype diversity and population data for Central Brazil: implications for environmental forensics and paternity testing
Autor: Vieira, Thaís Cidália
Gigonzac, Marc Alexandre Duarte
Silva, Daniela Melo e
Rodovalho, Ricardo Goulart
Santos, Gilberto de Souza
Cruz, Aparecido Divino da
Abstract: The central region of Brazil was colonized by internal migration of individuals of different origins, who contributed to the genetic diversity existing in this population. This study determined the allele frequencies and haplotype diversity of Y-STRs in Goiás State, Central Brazil, and compared the data obtained with a sample of the Brazilian population, consisting of individuals from the five geographical regions of Brazil. A total of 353 males were typed for 12 Y-chromosome short tandem repeat (Y-STR) markers. We selected males who had no degree of relatedness, from the five mesoregions of Goiás State. DNA was extracted from blood samples followed by the amplification of the 12 Y-chromosome loci. The products were analyzed to obtain the allele profiles on an ABI3500 automated sequencer using the Gene Mapper software. Allele frequencies and haplotype diversity were estimated by direct counting, and gene diversity for each locus was computed using the Arlequin software. The results are consistent with the history of miscegenation of the population of Central Brazil, in which we observed 321 different haplotypes. The average gene diversity at the 12 loci was 0.645. DYS385b and DYS389I showed the highest (0.704) and lowest (0.520) genetic diversity values, respectively. The FST value between the Brazilian and Goiás populations was 0.00951, showing no statistical significance. The results of this study allowed the establishment of haplotypes found in the forensic samples of Goiás State serving as a reference in the elucidation of criminal cases and paternity tests, as well as population and evolutionary inferences.
Palavras-chave: Y chromosome
STR markers
Haplotype diversity
País: Brasil
Unidade acadêmica: Instituto de Ciências Biológicas - ICB (RG)
Citação: VIEIRA, T. C.; GIGONZAC, M. A. D.; SILVA, D. M.; RODOVALHO, R. G.; SANTOS, G.S.; CRUZ, A. D. da. Y-STR haplotype diversity and population data for Central Brazil: implications for environmental forensics and paternity testing. Genetics and Molecular Research, Ribeirão Preto, v. 13, n. 2, p. 3404-3410, Apr. 2014.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.4238/2014.April.30.1
Identificador do documento: 10.4238/2014.April.30.1
URI: http://repositorio.bc.ufg.br/handle/ri/15522
Data de publicação: Abr-2015
Aparece nas coleções:ICB - Artigos publicados em periódicos

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