Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15524
Tipo do documento: Artigo
Título: Cytogenetic damage in the buccal epithelium of Brazilian aviators occupationally exposed to agrochemicals
Autor: Minasi, Lysa Bernardes
Costa, Emília Oliveira Alves
Silva, Daniela Melo e
Melo, Caroline Oliveira de Araújo
Almeida, Jonas Garcia de
Vieira, Thaís Cidália
Silva Júnior, Raimundo Lima da
Ribeiro, Cristiano Luiz
Silva, Cláudio Carlos da
Cruz, Aparecido Divino da
Abstract: The frequency of micronuclei in both buccal cells and peripheral blood lymphocytes is extensively used as a biomarker of chromosomal damage and genome stability in human populations. We examined whether prolonged exposure to complex mixtures of pesticides leads to an increase in cytogenetic damage. The exposed group comprised 50 agricultural aviators, mainly from Central and Southeast regions of Brazil, who had inhaled agrochemicals for more than 10 years without personal protection equipment; the control group consisted of 17 men from the same regions, without indication of exposure to pesticides, There were three times higher frequencies of micronuclei (P < 0.05) and 2.5 times higher frequencies of binucleated cells in the aviators when compared to controls. However, cytotoxic alterations such as broken eggs and karyorrhexis did not present statistically significant differences between the exposed and control groups. Therefore, diverse agrochemicals used to combat pests in agriculture possess genotoxic effects in the oral mucosa of the agricultural pilots, as showed in this study.
Palavras-chave: Genotoxic agents
Mutagenesis
Biomonitoring
Occupational exposure
País: Brasil
Unidade acadêmica: Instituto de Ciências Biológicas - ICB (RG)
Citação: MINASI, L. B.; COSTA, E .O. A.; SILVA, D. M.; MELO, C. O. A.; ALMEIDA, J. G. de; VIEIRA, T. C.; SILVA JÚNIOR, R. L.; RIBEIRO, C. L.; SILVA, C. C. da; CRUZ, A. D. da. Cytogenetic damage in the buccal epithelium of Brazilian aviators occupationally exposed to agrochemicals. Genetics and Molecular Research, Ribeirão Preto, v. 10, n. 4, p. 1-6, Dec. 2011.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.4238/2011.December.12.5
Identificador do documento: 10.4238/2011.December.12.5
URI: http://repositorio.bc.ufg.br/handle/ri/15524
Data de publicação: Dez-2010
Aparece nas coleções:ICB - Artigos publicados em periódicos

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