Inhibition of self-grooming induced by sleep restriction in dam rats
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Data
2012
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Resumo
Background & objectives: Sleep restriction is a common feature of modern lifestyle and its effects can be
extended to pregnancy. Several neurobehavioural consequences of sleep restriction during pregnancy
have been reported, among which stand out perinatal depression and maternal fatigue, however, its
effects over mother-infant relationship warrant further investigation. Thus, this study was aimed to
evaluate the effects of sleep restriction during pregnancy over maternal behaviour and maternal
aggression through animal models.
Methods: Eighteen 90-day-old female Wistar rats were distributed in two groups: (i) Control - not
submitted to any manipulation during pregnancy, and (ii) Sleep restriction - submitted to sleep restriction
during the entire pregnancy (21 days) through the multiple platforms technique. In the postpartum day
5, resident-intruder paradigm and the latencies test were performed to assess both maternal behaviour
and maternal aggression.
Results: The sleep-restricted females displayed grooming in less frequency and duration, and with
higher latency when compared to normal animals, while maternal aggression and maternal behaviour
parameters remained equivalent between groups.
Interpretation & conclusions: Considering the maintenance of maternal behavioural parameters, the
inhibition of grooming seems to exert an adaptive mechanism, enabling sleep-restricted rats to display
maternal behaviour properly
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Palavras-chave
Grooming, Maternal behavior, Pregnancy, Sleep restriction
Citação
PIRES, Gabriel Natan de Souza; ALVARENGA, Tathiana Aparecida; MAIA, Lucas Oliveira; COSTA, Renata Mazaro; TUFIK, Sérgio; ANDERSEN, Monica Levy . Inhibition of self-grooming induced by sleep restriction in dam rats. Indian Journal of Medical Research, Mumbai, v. 136, p. 1025-1030, Dec. 2012.