Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15578
Tipo do documento: Artigo
Título: The effect of carbon dioxide therapy on composite graft survival
Autor: Durães, Eliana Ferreira Ribeiro
Durães, Leonardo de Castro
Carneiro, Fabiana Pirani
Lino Junior, Ruy de Souza
Sousa, João Batista de
Abstract: PURPOSE: To investigate the effect of carboxytherapy in auricular composite grafts in rabbits. METHODS: An experimental study was conducted using 20 rabbits randomly assigned to a treatment group of carboxytherapy or a control group of saline solution. In each ear, a circular graft with 1.5 cm or 2 cm of diameter was amputated and reattached. Animals underwent carbon dioxide or saline injection four times during the experiment. We analyzed clinical evolution of the animals, grafts survival, histopathology features and histomorphometry of collagen. RESULTS: The treated group had a significantly lower weight gain (p=0.038). Histopathology was not significantly different between groups. There was an increase in amount of collagen in 2 cm grafts submitted to carbon dioxide therapy (p=0.003). Carboxytherapy didn’t influence graft survival rate for 1.5 cm grafts or 2 cm grafts (p=0.567 and p=0.777, respectively). CONCLUSIONS: Carbon dioxide therapy increased the amount of collagen in 2 cm grafts. CO 2 was not significantly different from saline infusion on composite grafts survival, but this study suggests that there is a mechanical effect caused by distension which favored graft survival.
Palavras-chave: Wound healing
Rabbits
Graft survival
Carbon dioxide
País: Brasil
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: DURÃES, Eliana Ferreira Ribeiro; DURÃES, Leonardo de Castro; CARNEIRO, Fabiana Pirani; LINO JÚNIOR, Ruy de Souza; SOUSA, João Batista de. The effect of carbon dioxide therapy on composite graft survival. Acta Cirúrgica Brasileira, São Paulo, v. 28, n. 8, p. 589-593, Aug. 2013.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S0102-86502013000800006
Identificador do documento: 10.1590/S0102-86502013000800006
URI: http://repositorio.bc.ufg.br/handle/ri/15578
Data de publicação: Ago-2013
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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