Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/15835
Tipo do documento: Artigo
Título: Obtaining a dry extract of pterodon emarginatus (Fabaceae) fruits by spray-drying
Autor: Oliveira, Patrícya Caixeta de
Conceição, Edemilson Cardoso da
Oliveira, Patricia Abrão de
Nascimento, Marcos Vinícius
Costa, Elson Alves
Paula, José Realino de
Bara, Maria Teresa Freitas
Abstract: The Pterodon emarginatus presents some pharmacological properties that may be related to the presence of vouacapanes. The purpose of this work is to reach a standardized dry extract of the P. emarginatus fruit. The powder, ethanolic extract and dry extract showed the presence of vouacapanes and lupeol confirmed by IR and GC-MS. The drying process (spray drying) using the colloidal silicon dioxide showed to prevent the thermal degradation and increased approximately twice the terpenes content. The scanning electron microscopy (SEM) showed irregular and spherical particles. The analytical method by spectrophotometry for the quantification of total terpenes was validated and showed to be selective, linear, precise, accurate and robust. In the antinociceptive activity test (capsaicin), the pre-treatment with the dried extract reduced the reactivity time in 50.9%. The results may suggest that the technological processes employed to transform the P. emarginatus fruits in standardized dried extract were adequate to maintain quality chemistry and antinociceptive activity described for the fruits. This work represents the first description of the obtaining of the standardized dried extract of P. emarginatus and also the identification of lupeol in the fruits of this medicinal plant.
Palavras-chave: Medicinal plant
Antinociceptive
Quality control
Spray drying
Technological processes
País: Outros
Unidade acadêmica: Instituto de Ciências Biológicas - ICB (RG)
Citação: OLIVEIRA,Patrícya C. et al. Obtaining a dry extract of pterodon emarginatus (Fabaceae) fruits by spray-drying. Journal of Pharmacy Research,  Kharar, v. 5, n. 1, p. 641-645, Jan. 2012.
Tipo de acesso: Acesso Aberto
URI: http://repositorio.bc.ufg.br/handle/ri/15835
Data de publicação: Jan-2012
Aparece nas coleções:ICB - Artigos publicados em periódicos

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