Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/16241
Tipo do documento: Artigo
Título: Oral midazolam reduces cortisol levels during local anaesthesia in children: a randomised controlled trial
Autor: Rodrigues, Heloisa de Sousa Gomes
Faria, Patricia Corrêa de
Silva, Tarcília Aparecida da
Paiva, Saul Martins de
Costa, Paulo Sérgio Sucasas da
Batista, Aline Carvalho
Costa, Luciane Ribeiro de Rezende Sucasas da
Abstract: Little is known about whether midazolam sedation can reduce salivary cortisol levels and consequently influence children’s behaviour during dental treatment. The aim of this study was to evaluate the effect of midazolam sedation on salivary cortisol and its correlation with children’s behaviour during restorative dental treatment. Eighteen healthy children, aged two to five years, were randomly assigned to two dental treatment appointments, both with physical restraint: oral midazolam 1 mg/kg (MS) and placebo (PS). An observer assessed the children’s behaviour (videos) using the Ohio State University Behavioral Rating Scale (OSUBRS). The children’s saliva was collected just after waking up, on arrival at the dental school, 25 minutes after local anaesthesia, and 25 minutes after the end of the procedure. Salivary cortisol levels were determined using the enzyme-linked immunoabsorbent assay. The data were analysed by bivariate tests and multivariate analysis of variance (5% level). Salivary cortisol levels were lower in the MS group than in the PS group at the time of anaesthesia (p = 0.004), but did not vary during the appointment within sedation (p = 0.319) or placebo (p = 0.080) groups. Children’s behaviour was negative most of the time and did not differ between MS and PS; however, the behaviour (OSUBRS) did not correlate with salivary cortisol levels. Oral midazolam is able to control salivary cortisol levels during dental treatment of pre-schoolers, which might not lead to better clinical behaviour.
Palavras-chave: Saliva
Dental anxiety
Hydrocortisone
Midazolam
Child behaviour
País: Brasil
Unidade acadêmica: Faculdade de Odontologia - FO (RG)
Citação: GOMES, Heloisa Sousa et al. Oral midazolam reduces cortisol levels during local anaesthesia in children: a randomised controlled trial. Brazilian oral research, São Paulo, v. 29, p. 1-9, 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/1807-3107BOR-2015.vol29.0125
Identificador do documento: 10.1590/1807-3107BOR-2015.vol29.0125
URI: http://repositorio.bc.ufg.br/handle/ri/16241
Data de publicação: 2015
Aparece nas coleções:FM - Artigos publicados em periódicos

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