Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/16290
Tipo do documento: Artigo
Título: Influence of Beta-2-Adrenergic receptor Gln27Glu polymorphism on the autonomic heart rate modulation in young sedentary and physically active women
Autor: Rebelo, Ana Cristina Silva
Melo, Aryanne Batista Soares de
Salviati, Mariana Rodrigues
Verlengia, Rozangela
Vale, Arthur Ferreira do
Nogueira, Yanley Lucio
Tamburús, Nayara Yamada
Kunz, Vandeni Clarice
Silva, Ester da
Resumo: Background: Studies have shown an interaction between the autonomic heart rate (HR) modulation and genetic polymorphisms. Nevertheless, it is yet unclear how a particular genetic polymorphism may determine a pattern of autonomic HR control, especially regarding the role of physical exercise. The objective was to investigate the influence of of Beta-2- Adrenergic (β2-AR) Gln27Glu polymorphisms and exercise on HRV of young Brazilian women. Methods: The group was selected as Sedentary Group (SG; n = 88) and physically Active Group (AG; n = 99). The β2-AR polymorphisms were analyzed using PCR-RFLP. The amplicons were subjected to electrophoresis on a 10% acrylamide gel and stained with ethidium bromide. The HR was registered in real time for 15 minutes, in the supine-position. The heart rate variability (HRV) was analysed using Shannon’s entropy (SE), conditional entropy (complexity index [CInd] and normalized CInd [NCI]), and symbolic analysis (0V%, 1V%, 2LV%, and 2ULV%). Statistical analysis: Analysis of variance (ANOVA) with Fisher's Least. Results: AG presented higher values for SE and 2ULV%, and lower values for 0V% when compared to SG (p<0.05). There was no significant difference of any index among genotypes both from the complexity and symbolic analysis. The interaction between genotype and exercise did not significantly affect HRV. Conclusion: These results do not support the concept that the β2-AR Gln27Glu polymorphisms affects the HRV indexes in physically active or sedentary women.
Palavras-chave: β 2 -Adrenergic polymorphism
Women
Exercise
Heart rate variability
Non-linear analysis
País: Estados unidos
Unidade acadêmica: Instituto de Ciências Biológicas - ICB (RG)
Citação: REBELO, Ana Cristina Silva. Influence of Beta-2-Adrenergic receptor Gln27Glu polymorphism on the autonomic heart rate modulation in young sedentary and physically active women. American Journal of BioScience, New York, v. 3, n. 5, p. 190-196, 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.11648/j.ajbio.20150305.15
Identificador do documento: 10.11648/j.ajbio.20150305.15
URI: http://repositorio.bc.ufg.br/handle/ri/16290
Data de publicação: 2015
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