Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/16352
Tipo do documento: Artigo
Título: A preliminary study of the antibacterial potential of cetylpyridinium chloride in root canals infected by E. faecalis
Autor: Estrela, Carlos
Sousa Neto, Manoel Damião de
Alves, Denise Ramos Silveira
Alencar, Ana Helena Gonçalves de
Santos, Tatiane Oliveira
Pécora, Jesus Djalma
Abstract: The aim of this preliminary study was to verify the antibacterial potential of cetylpyridinium chloride (CPC) in root canals infected by Enterococcus faecalis. Forty human maxillary anterior teeth were prepared and inoculated with E. faecalis for 60 days. The teeth were randomly assigned to the following groups: 1: Root canal preparation (RCP) + 0.1% CPC with positive-pressure irrigation (PPI, Conventional, NaviTip ® ); 2: RCP + 0.2% CPC PPI; 3: RCP + 2.5% NaOCl PPI; 4: RCP + 2.5% NaOCl with negative-pressure irrigation system (NPI, EndoVac ® ); 5: Positive control; and 6: Negative control. Four teeth of each experimental group were evaluated by culture and 4 by scanning electron microscopy (SEM). In all teeth, the root canals were dried and filled with 17% EDTA (pH 7.2) for 3 min for smear layer removal. Samples from the infected root canals were collected and immersed in 7 mL of Letheen Broth (LB), followed by incubation at 37°C for 48 h. Bacterial growth was analyzed by turbidity of culture medium and then observed with a UV spectrophotometer. The irrigating solutions were further evaluated for antimicrobial effect by an agar diffusion test. The statistical data were treated by means, standard deviation, Kruskal-Wallis test and analysis of variance. Significance level was set at 5%. The results showed the presence of E. faecalis after root canal sanitization. The number of bacteria decreased after the use of CPC. In the agar diffusion test, CPC induced large microbial inhibition zones, similar to 2% chlorhexidine and large than 2.5% NaOCl. In conclusion, cetylpyridinium chloride showed antibacterial potential in endodontic infection with E. faecalis.
Palavras-chave: Cetylpyridinium chloride
E. faecalis
Sodium hypochlorite
Quaternary ammonium
Chlorhexidine
País: Brasil
Unidade acadêmica: Faculdade de Odontologia - FO (RG)
Citação: ESTRELA, Carlos et al. A preliminary study of the antibacterial potential of cetylpyridinium chloride in root canals infected by E. faecalis. Brazilian Dental Journal, Ribeirão Preto, v. 23, n. 6, p. 645-653, 2012.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S0103-64402012000600004
Identificador do documento: 10.1590/S0103-64402012000600004
URI: http://repositorio.bc.ufg.br/handle/ri/16352
Data de publicação: 2012
Aparece nas coleções:FM - Artigos publicados em periódicos

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