Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/16702
Tipo do documento: Artigo
Título: Economic impact of dengue: multicenter study across four brazilian regions
Autor: Martelli, Celina Maria Turchi
Siqueira Júnior, Jãoo Bosco
Parente, Mirian Perpetua Palha Dias
Zara, Ana Laura de Sene Amancio
Oliveira, Consuelo Silva
Braga, Cynthia
Pimenta Júnior, Fabiano Geraldo
Cortes, Fanny
Lopez, Juan Guillermo
Bahia, Luciana Ribeiro
Mendes, Marcia Costa Ooteman
Rosa, Michelle Quarti Machado da
Siqueira Filha, Noemia Teixeira de
Constenla, Dagna
Souza, Wayner Vieira de
Abstract: Background Dengue is an increasing public health concern in Brazil. There is a need for an updated evaluation of the economic impact of dengue within the country. We undertook this multi-center study to evaluate the economic burden of dengue in Brazil. Methods We estimated the economic burden of dengue in Brazil for the years 2009 to 2013 and for the epidemic season of August 2012- September 2013. We conducted a multicenter cohort study across four endemic regions: Midwest, Goiania; Southeast, Belo Horizonte and Rio de Janeiro; Northeast: Teresina and Recife; and the North, Belem. Ambulatory or hospital-ized cases with suspected or laboratory-confirmed dengue treated in both the private and public sectors were recruited. Interviews were scheduled for the convalescent period to ascertain characteristics of the dengue episode, date of first symptoms/signs and recovery, use of medical services, work/school absence, household spending (out-of-pocket expense) and income lost using a questionnaire developed for a previous cost study. We also extracted data from the patients’ medical records for hospitalized cases. Overall costs per case and cumulative costs were calculated from the public payer and societal perspec- tives. National cost estimations took into account cases reported in the official notification system (SINAN) with adjustment for underreporting of cases. We applied a probabilistic sensitivity analysis using Monte Carlo simulations with 90% certainty levels (CL).Results We screened 2,223 cases, of which 2,035 (91.5%) symptomatic dengue cases were included in our study. The estimated cost for dengue for the epidemic season (2012–2013) in the societal perspective was US$ 468 million (90% CL: 349–590) or US$ 1,212 million (90% CL: 904–1,526) after adjusting for under-reporting. Considering the time series of den-gue (2009–2013) the estimated cost of dengue varied from US$ 371 million (2009) to US$ 1,228 million (2013). Conclusions The economic burden associated with dengue in Brazil is substantial with large variations in reported cases and consequently costs reflecting the dynamic of dengue transmission.
País: Estados unidos
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: MARTELLI, Celina Maria Turchi et al. Economic impact of dengue: multicenter study across four brazilian regions. PLoS Neglected Tropical Diseases, San Francisco, v. 9, n. 9, p. e0004042, 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1371/journal. pntd.0004042
Identificador do documento: 10.1371/journal. pntd.0004042
URI: http://repositorio.bc.ufg.br/handle/ri/16702
Data de publicação: 24-Set-2015
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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