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dc.creatorOliveira, Luciana Alves de-
dc.creatorMartins, Regina Maria Bringel-
dc.creatorCarneiro, Megmar Aparecida dos Santos-
dc.creatorTeles, Sheila Araujo-
dc.creatorSilva, Simonne Almeida e-
dc.creatorCardoso, Divina das Dôres de Paula-
dc.creatorLampe, Elisabeth-
dc.creatorYoshida, Clara Fumiko Tachibana-
dc.date.accessioned2019-01-15T14:50:03Z-
dc.date.available2019-01-15T14:50:03Z-
dc.date.issued2002-10-
dc.identifier.citationOLIVEIRA, Luciana A.; MARTINS, Regina M. B.; CARNEIRO, Megmar A. S.; TELES, Sheila A.; SILVA, Simonne A.; CARDOSO, Divina D. P.; LAMPE, Elisabeth; YOSHIDA, Clara F. T. Prevalence and genotypes GB virus C/ Hepatitis G virus among blood donors in central Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 97, n. 7, p. 953-957, 2002.pt_BR
dc.identifier.issn0074-0276-
dc.identifier.issne- 1678-8060-
dc.identifier.urihttp://repositorio.bc.ufg.br/handle/ri/16733-
dc.description.abstractA survey was conducted in a blood donor population of Central Brazil aiming to investigate the prevalence of GB virus C (GBV-C)/hepatitis G virus (HGV) infection and also to analyze the virus genotypes distribution. A total of 241 voluntary blood donors were interviewed at the State Blood Bank in Goiânia, State of Goiás, Brazil. Blood samples were collected and serum samples tested for GBV-C/HGV RNA by polymerase chain reaction. Genotypes were determined by restriction fragment length polymorphism (RFLP) analysis. Seventeen samples were GBV-C/HGV RNA-positive, resulting in a prevalence of 7.1% (95% CI: 4.2-11.1). A significant trend of GBV-C/HGV RNA positivity in relation to age was observed, with the highest prevalence in donors between 29-39 years old. Ten infected individuals were characterized by reporting parenteral (30%), sexual (18%), both (6%) and intrafamiliar (6%) transmission. However, 7 (40%) GBV-C/HGV RNA-positive donors did not mention any potential transmission route. RFLP analysis revealed the presence of genotypes 1 and 2 of GBV-C/HGV; more precisely, 10 (58.9%) samples were found belonging to the 2b subtype, 4 (23.5%) to the 2a subtype, and 3 (17.6%) to genotype 1. The present data indicate an intermediate endemicity of GBV-C/HGV infection among this blood donor population, and a predomi-nant circulation of genotype 2 (subtype 2b) in Central Brazil.pt_BR
dc.language.isoengpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCentral Brazilpt_BR
dc.subjectHepatitis G viruspt_BR
dc.subjectGB virus Cpt_BR
dc.subjectBlood donorspt_BR
dc.subjectGoiâniapt_BR
dc.titlePrevalence and genotypes GB virus C/ Hepatitis G virus among blood donors in central Brazilpt_BR
dc.typeArtigopt_BR
dc.publisher.countryBrasilpt_BR
dc.identifier.doi10.1590/S0074-02762002000700005-
dc.publisher.departmentInstituto de Patologia Tropical e Saúde Pública - IPTSP (RG)pt_BR
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