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Tipo do documento: Artigo
Título: Epidemiology of early-onset dementia: a review of the literature
Autor: Vieira, Renata Teles
Caixeta, Leonardo Ferreira
Machado, Sérgio
Silva, Adriana Cardoso
Nardi, Antônio Egídio
Arias-Carrión, Oscar
Carta, Mauro Giovanni
Abstract: Presenile Dementia or Early Onset Dementia (EOD) is a public health problem, it differs from Senile Demen-tia, and encloses a significant number of cases; nevertheless, it is still poorly understood and underdiagnosed. This study aims to review the prevalence and etiology of EOD, comparing EOD with Senile Dementia, as well as to show the main causes of EOD and their prevalence in population and non-population based studies. The computer-supported search used the following databases: Pubmed/Medline, ISI Web of Knowledge and Scielo. The search terms were alcohol-associated dementia, Alzheimer’s disease, dementia, Creutzfeldt-jakob disease, dementia with lewy bodies, early onset dementia, frontotemporal lobar degeneration, Huntington’s disease, mixed dementia, neurodegenerative disorders, Parkinson’s dis-ease dementia, presenile dementia, traumatic brain injury, vascular dementia. Only papers published in English and con-ducted from 1985 up to 2012 were preferentially reviewed. Neurodegenerative diseases are the most common etiologies seen in EOD. Among the general population, the prevalence of EOD was found to range between 0 to 700 per 100.000 habitants in groups of 25-64 years old, with an increasing incidence with age. The progression of EOD was found to range between 8.3 to 22.8 new cases per 100.000 in those aged under 65 years. Alzheimer's disease (AD) is the major etiology, followed by Vascular Dementia (VaD) and Frontotemporal Lobar Degeneration (FTLD). A larger number of epidemiol-ogical studies to elucidate how environmental issues contribute to EOD are necessary, thus, we can collaborate in the planning and prevention of services toward dementia patients.
Palavras-chave: VaD
Alzheimer’s disease
Early onset dementia
Frontotemporal lobar degeneration
Neurodegenerative disorders
Presenile dementia
Vascular dementia
País: Gra-bretanha
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: VIEIRA, Renata Teles; CAIXETA, Leonardo; MACHADO, Sergio; SILVA, Adriana Cardoso; NARDI, Antonio Egidio; ARIAS-CARRIÓN, Oscar; CARTA, Mauro Giovanni. Epidemiology of early-onset dementia: a review of the literature. Clinical Practice and Epidemiology in Mental Health, London, v. 9, p. 88-95, 2013.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.2174/1745017901309010088
Identificador do documento: 10.2174/1745017901309010088
Data de publicação: 2013
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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