Determinação da atividade antibacteriana e toxicidade do ácido acético e vinagres branco e tinto
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Data
2007-12
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Editor
Marize Campos Valadares
Resumo
Acetic acid and vinegar have a long history and human applicability, including the clinical treatment of
wounds. The aim of this study was to evaluate in vitro antibacterial activity and toxicity of acetic acid and white and
red vinegars. The antibacterial activity was evaluated by Maximum Inhibitory Dilution (MID) of acetic acid and
vinegars against hospital bacteria: Pseudomonas aeruginosa (20), Escherichia coli (20), Staphylococcus aureus
(20), and the toxicity based on the mortality percentage of Artemia salina Leach. The MIDs of acetic acid against
P.aeruginosa, E.coli and S.aureus were at 1:400. Moreover, the white and red vinegars inhibited all E. coli and S.
aureus at 1:50 and 1:33, respectively. However, the red and white vinegars showed MIDs against P. aeruginosa at
1:67 and 1:50, respectively. The acetic acid in natura, 1:50, 1:100, 1:200, 1:400 e 1:800 demonstrated toxicity
against A. salina Leach. Both white and red vinegars did not show toxicity at 1:400 and 1:800. In conclusion, it is
possible to consider that there is an inverted proportional relation of the acetic acid and vinegars dilutions, with the
antibacterial activity and the toxicity. Besides, this study provides some relevant technical information that can
elucidate about risks of inadequate use (dilution/concentration) these products in vivo, specially, on wounds.
Descrição
Palavras-chave
Ácido acético, Testes de sensibilidade microbiana, Toxicidade, Cicatrização de feridas, Acetic acid, Microbial sensitivity tests, Toxicity, Wound healing
Citação
UTYAMA, Iwa Keiko Aida; ANDRADE, Denise de; WATANABE, Evandro; PIMENTA, Fabiana Cristina; ITO, Izabel Yoko. Determinação da atividade antibacteriana e
toxicidade do ácido acético e vinagres branco e tinto. Revista Eletrônica de Farmácia, Goiânia, v. 4, n. 1, p. 104-112, jan./jun. 2007. Disponível em: <https://revistas.ufg.br/REF/article/view/3054/3090>.