Desenvolvimento e validação de método analítico espectrofotométrico para doseamento de furosemida matéria-prima
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Data
2009-06
Título da Revista
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Título de Volume
Editor
Ricardo Menegatti
Resumo
The furosemide is a drug that acts as diuretic been used to treat arterial hypertension.
Among the methods used for their determination, there is the possibility of quantification
of furosemide by spectrophotometrics methods, for presenting good sensitivity and have
more affordable cost. This study aimed to develop and validate an analytical
methodology for determination of this drug in raw material, using ultraviolet
spectrophotometry. The method employed proved to be simple, rapid, specific, linear,
accurate, precise and robust to run in a routine of a laboratory of quality control, being
an alternative to procedures used. By applying the method developed in this study for
the analysis of a oral solution of furosemide it was noted the need and importance of
validating the analytical protocol in accordance with the formulation produced..
Descrição
Palavras-chave
Furosemida, Controle de qualidade, Espectrofotometria, Metodologia analítica, Validação, Furosemide, Quality control, Spectrophotometry, Analytical methodology, Validation
Citação
DUARTE, Lívia Teixeira; SILVA, Ezequiane Machado; MIRANDA, Cláudia Gomes; LOPES, Emilia Ferreira; MORAIS, Hanna Lopes; LOBO, Izabella; GARROTE, Clévia Ferreira Duarte; BARA, Maria Teresa Freitas. Desenvolvimento e validação de método analítico
espectrofotométrico para doseamento de furosemida matéria-prima. Revista Eletrônica de Farmácia, Goiânia, v. 6, n. 2, p. 72-84, abr./jun. 2009. Disponível em: <https://revistas.ufg.br/REF/article/view/6548/4807>.