Ausência de atividade mutagênica de guazuma ulmifolia lamb. (mutamba) em células somáticas de drosophila melanogaster
Carregando...
Data
2006-12
Título da Revista
ISSN da Revista
Título de Volume
Editor
Vera Lúcia Gomes Klein
Resumo
Guazuma ulmifolia Lamb. is a medicinal plant, locally called “mutamba”, which grows in the Cerrado of Brazil. Mutamba phytotherapic is used in alternative medicine to treat diarrhea, asthma, bronchitis, fever, elephantiasis, syphilis, obesity, leprosy, hairlass, dysentery, among others. This phytothergric agent is also used as astringent, depurative, and sudorific. This study evaluated the genotoxic effect of the mutamba through somatic mutation and recombination test (SMART/wing) in the third instar of Drosophila melanogaster larvae resulting from the standard cross (ST) and high bioactivation cross (HB). There were no statistically significant alterations in the frequencies of spot among different concentrations of the phytoterapic (500, 50, 35, 25 mg/mL) to the negative control for the descendents of all crosses. This suggests that G. ulmifolia had no genotoxic effects in somatic cells of D. melanogaster in these conditions.
Descrição
Palavras-chave
Citotóxico, Genotóxico, Mutamba, Guazuma, Malvacese, Citotoxic, Genotoxic
Citação
SILVA, Cristiano José da; FERREIRA, Heleno Dias; FERRI, Pedro Henrique; NUNES, Wanderlene Blanco; PEREIRA, Denise Gonçalves; CARVALHO, Salvador de. Ausência de atividade mutagênica de guazuma ulmifolia lamb. (mutamba) em células somáticas de drosophila melanogaster. Revista de Biologia Neotropical, Goiânia, v. 3, n. 2, p. 163-168, jul.dez. 2006. Disponível em: <https://www.revistas.ufg.br/RBN/article/view/2621/2834>.