Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/16972
Tipo do documento: Artigo
Título: Congenital transmission of Trypanosoma cruzi in central Brazil. A study of 1,211 individuals born to infected mothers
Autor: Ostermayer, Alejandro Luquetti
Tavares, Suelene Brito do Nascimento
Siriano, Liliane da Rocha
Oliveira, Rozângela Amaral de
Campos, Dayse Elizabeth
Moraes, Cicilio Alves de
Oliveira, Enio Chaves de
Abstract: Transmission of Trypanosoma cruzi during pregnancy is estimated to occur in less than 20% of infected moth- ers; however, the etiopathogenesis is not completely understood. The Centre for Studies on Chagas Disease pro- vides confirmation of T. cruzi infection for individuals living in central Brazil. In this retrospective hospital-based study, all requests for diagnosis of T. cruzi infection in individuals less than 21 years old from 1994-2014 were searched. We end with 1,211 individuals and their respective infected mothers. Congenital transmission of infec- tion was confirmed in 24 individuals (2%) in central Brazil, an area where the main T. cruzi lineage circulating in humans is TcII. This low prevalence of congenital Chagas disease is discussed in relation to recent findings in the south region of Brazil, where TcV is the main lineage and congenital transmission has a higher prevalence (approximately 5%), similar to frequencies reported in Argentina, Paraguay and Bolivia. This is the first report to show geographical differences in the rates of congenital transmission of T. cruzi and the relationship between the prevalence of congenital transmission and the type of Tc prevalent in each region.
Palavras-chave: Chagas disease
Familial studies
Trypanosoma cruzi
Geographical differences
País: Brasil
Unidade acadêmica: Faculdade de Medicina - FM (RG)
Citação: LUQUETTI, Alejandro O. et al. Congenital transmission of Trypanosoma cruzi in central Brazil. A study of 1,211 individuals born to infected mothers. Memorias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 110, n. 3, p. 369-376, May 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/0074-02760140410
Identificador do documento: 10.1590/0074-02760140410
URI: http://repositorio.bc.ufg.br/handle/ri/16972
Data de publicação: Mai-2015
Aparece nas coleções:FM - Artigos publicados em periódicos

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