Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/17411
Tipo do documento: Artigo
Título: Health care workers humoral immune response against GLcB, MPT51 and HSPX from Mycobacterium tuberculosis
Autor: Reis, Michelle Cristina Guerreiro dos
Rabahi, Marcelo Fouad
Kipnis, André
Junqueira-Kipnis, Ana Paula
Abstract: Tuberculosis (TB) is one of the oldest human infectious diseases and one third of the world’s population is latently infected. Brazil is an endemic area for TB. One of the most important challenges in TB control is the identification of latently infected individuals. Health Care Workers (HCW) are at high risk of being infected with Mycobacterium tuberculosis and even to become TB latently infected. The aim of this study was to increase knowledge about humoral immune response in TB latently infected individuals. HCW were classified according to their tuberculin skin test (TST), as positive or negative. The antibody response to GLcB, MPT51 and HSPX from Mycobacterium tuberculosis was evaluated. TST negative HCW constituted the majority of those who showed a humoral immune response. Antibody levels varied according to antigen characteristics, TST and BCG status. We suggest that possibly the presence of those antibodies could have a function in the protective immune response against Mycobacterium tuberculosis.
Palavras-chave: Latent tuberculosis
Antibodies
Infection
País: Brasil
Unidade acadêmica: Faculdade de Medicina - FM (RG)
Citação: REIS, Michelle Cristina Guerreiro dos et al. Health care workers humoral immune response against GLcB, MPT51 and HSPX from Mycobacterium tuberculosis. Brazilian Journal of Infectious Diseases, Salvador, v. 13, n. 6, p. 417-421, Dec. 2009.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S1413-86702009000600006
Identificador do documento: 10.1590/S1413-86702009000600006
URI: http://repositorio.bc.ufg.br/handle/ri/17411
Data de publicação: Dez-2009
Aparece nas coleções:FM - Artigos publicados em periódicos

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