Retinopatia em paciente portador de hepatite C tratado com interferon peguilado e ribavirina: relato de caso
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Data
2006
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Resumo
Interferon is an immunomodulating cytokine used to treat
patients with different diseases, such as hepatitis C chronic
infection. Pegylated interferon is a new type of interferon,
developed to increase the half-life of the drug. Many side
effects have been related to its use, including ocular toxicity
and retinopathy. The most reported ocular findings are
cotton-wool spots and hemorrhages located at the posterior
pole and surrounding optic nerve head. We describe one case
of pegylated interferon-associated retinopathy with visual
loss. The patient had visual acuity improvement four weeks
after discontinuation of the medication and the ocular fin-
dings became much more subtle.
Descrição
Palavras-chave
Hepatite C/quimioterapia, Interferon alfa-2a/uso terapêutico, Ribavirina/uso terapêutico, Quimioterapia combinada, Retina/efeitos de drogas, Acuidade visual, Retinite pigmentosa/ etiologia, Relatos de casos [tipo de publicação], Acuidade visual, Retinite pigmentosa/ etiologia, Hepatitis C/drug therapy, Case reports [publication type], Interferon alfa-2a/therapeutic use, Visual acuity, Ribavirin/therapeutic use, Retinitis pigmentosa/etiology, Drug therapy, combination, Retina/drug effects
Citação
ÁVILA, Marcos Pereira de et al. Retinopatia em paciente portador de hepatite C tratado com interferon peguilado e ribavirina: relato de caso. Arquivos Brasileiros de Oftalmologia, São Paulo, v. 69, n. 2, p. 255-259, 2006.