Anti-inflammatory and anti-nociceptive effects of Pterodon emarginatus stem bark alcohol extract

Resumo

The tail flick, the acetic acid writhing, the croton oil-induced mouse ear edema, and carrageenan-induced peritonitis tests were used to study the anti-inflammatory effects of the alcohol extract from Pterodon emarginatus Vogel. (Leguminosae/Fabaceae) stem bark. The alcohol extract caused inhibition of acetic acid-induced abdominal writhing, reducing the number of leukocytes (x 10 7 ) per mL of peritoneal wash and ear edema formation. The results suggest that Pterodon emarginatus stem bark contains compounds with analgesic and anti-inflammatory actions.

Descrição

Palavras-chave

Pterodon emarginatus, Carrageenan-induced peritonitis, Analgesic activity, Anti-inflammatory activity, Acetic acid-induced abdominal writhing

Citação

MORAES, Weuller F. de et al. Anti-Inflammatory and anti-nociceptive effects of pterodon emarginatus stem-bark alcohol extract. Pharmaceutical Biology, Abingdon, v. 47, n. 2, p. 146-150, 2009.