Seroprevalence of hepatitis B virus infection and associated factors among prison inmates in state of Mato Grosso do Sul, Brazil
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2010-10
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Resumo
Introduction: This study aimed to estimate the prevalence of HBV infection and associated
factors among prison inmates in Campo Grande, MS. Methods: A total of 408 individuals
were interviewed regarding sociodemographic characteristics, associated factors and HBV
vaccination using a standardized questionnaire. Blood samples were collected from all
participants and serological markers for HBV were detected by enzyme-linked immunosorbent
assay. Hepatitis B surface antigen (HBsAg) and/or antibodies against hepatitis B core antigen
(anti-HBc) positive samples were tested for HBV-DNA by polymerase chain reaction. Results:
The overall prevalence of HBV infection was 17.9% (95%CI: 14.4-22.0). The HBsAg carrier
rate was 0.5%; 56 (13.7%) individuals had been infected and developed natural immunity and
15 (3.7%) were positive for anti-HBc only. Ninety eight (24%) prisoners had only anti-HBs,
suggesting that they had low vaccine coverage. An occult HBV infection rate of 0% was verified
among anti-HBc-positive individuals. Multivariate analysis of associated factors showed that
age > 35 years-old, low schooling level and illicit drug use are significantly associated with
HBV infection. Conclusions: Analysis of the data showed HBV infection prevalence similar
or slightly lower than that reported in other of Brazilian prisons. Independent predictors of
HBV infection in this population include older age, low schooling level and illicit drug use.
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Hepatitis B, Prisoners, Prevalence, Associated factors, Hepatite B, Prevalência, Encarcerados, Fatores associados
Citação
STIEF, Alcione Cavalheiro Faro et al. Seroprevalence of hepatitis B virus infection and associated factors among prison inmates in State of Mato Grosso do Sul, Brazil. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 43, n. 5, p. 512-515, set./out. 2010.