Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/18245
Tipo do documento: Artigo
Título: HPV infection and cervical neoplasia: associated risk factors
Autor: Ribeiro, Andrea Alves
Costa, Maria Cecilia Martins
Alves, Rosane Ribeiro Figueiredo
Villa, Luísa Lina
Saddi, Vera Aparecida
Carneiro, Megmar Aparecida dos Santos
Zeferino, Luiz Carlos
Santos, Silvia Helena Rabelo dos
Abstract: Background: Behavioral risks such as age at first sexual intercourse, number of sexual partners and partner’s sexual behavior are associated with an increased risk of HPV infection, persistence of the infection and the development of neoplastic precursor lesions. The objective of this study was to evaluate the risk factors associated with HPV positivity and with a diagnosis of cervical neoplasia in women referred with an abnormal cervical smear. Methods: This study evaluated a series of 198 women referred with an abnormal cervical smear. Risk factors for HPV infection were investigated using a questionnaire. All cervical specimens were tested for 27 HPV genotypes using the Roche polymerase chain reaction reverse line blot assay. Results: The overall prevalence of HPV was 87 %. First sexual intercourse before 16 years of age was significantly associated with a positive HPV test (OR 4.41; 95 %CI: 1.20 − 19.33; p = 0.01). A significant association was also found between this risk factor and CIN 1 lesions or worse (OR 2.2; 95 %CI 0.94 − 5.08; p = 0.03). Conclusions: The age at which a woman begins to be sexually active is associated with HPV infection and with a diagnosis of cervical neoplasia.
Palavras-chave: Human papillomavirus
Risk factors
Abnormal cervical smear
País: Estados unidos
Unidade acadêmica: Faculdade de Medicina - FM (RG)
Citação: RIBEIRO, Andrea Alves et al. HPV infection and cervical neoplasia: associated risk factors. Infectious Agents and Cancer, New York, v. 10, n. 16, p. 1-8, 2015.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1186/s13027-015-0011-3
Identificador do documento: 10.1186/s13027-015-0011-3
URI: http://repositorio.bc.ufg.br/handle/ri/18245
Data de publicação: 2015
Aparece nas coleções:FM - Artigos publicados em periódicos

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