Isoniazid-resistant tuberculous spondylodiscitis associated with scrofuloderma
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Data
2018-12
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Editor
Ruy de Souza Lino Junior
Resumo
The extrapulmonary forms of tuberculosis are responsible for about 20% of cases.
Scrofuloderma is the cutaneous manifestation secondary to infection in some subcutaneous
foci. A 33-year-old patient was admitted to the Clinical Hospital with exudative skin lesions
on the back and thorax, initiated 10 months previously, associated with daily fever, and
constipation. Spine resonance showed a paravertebral pseudotumoral lesion with T4 and T9
invasion, including vertebral canal and sub-ligament extension. The lesions presented fistulas
for paravertebral muscles, lung and skin. Polimerase chain reaction (PCR) proved positive
for Mycobacterium tubeculosis in the thorax wound secretion, caracterizing tuberculous
spondilodiscitis with scrofuloderma. Treatment was initiated with rifampicin, isoniazid,
pyrazinamide and ethambutol with important clinical improvement after the first week. The
febrile peaks came to an end and there was improvement in the pattern of the cutaneous lesions.
The susceptibility test showed resistance to isoniazid.
Descrição
Palavras-chave
Extrapulmonary tuberculosis, Tberculous spondilodiscitis, Scrofuloderma
Citação
SALES, Luiz Felipe Silveira; CALÁBRIA, Murilo Fraga Oliveira; COSTA, Erika Barcelos; KIPNIS, André, BORGES, Moara Alves Santa Bárbara; SOUZA, Marta Antunes de; GUILARDE, Adriana Oliveira. Isoniazid-resistant tuberculous spondylodiscitis associated with
Scrofuloderma. Revista de Patologia Tropical, Goiânia, v. 47, n. 4, p. 247-253, out./dez. 2018. Disponível em: https://www.revistas.ufg.br/iptsp/article/view/56745.