Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/18367
Tipo do documento: Artigo
Título: Echocardiographic parameters and survival in chagas heart disease with severe systolic dysfunction
Autor: Frota, Daniela do Carmo Rassi
Vieira, Marcelo Luiz Campos
Arruda, Ana Lúcia Martins
Hotta, Viviane Tiemi
Furtado, Rogério Gomes
Rassi, Danilo Teixeira
Rassi, Salvador
Abstract: Background: Echocardiography provides important information on the cardiac evaluation of patients with heart failure. The identification of echocardiographic parameters in severe Chagas heart disease would help implement treatment and assess prognosis. Objective: To correlate echocardiographic parameters with the endpoint cardiovascular mortality in patients with ejection fraction < 35%. Methods: Study with retrospective analysis of pre-specified echocardiographic parameters prospectively collected from 60 patients included in the Multicenter Randomized Trial of Cell Therapy in Patients with Heart Diseases (Estudo Multicêntrico Randomizado de Terapia Celular em Cardiopatias) – Chagas heart disease arm. The following parameters were collected: left ventricular systolic and diastolic diameters and volumes; ejection fraction; left atrial diameter; left atrial volume; indexed left atrial volume; systolic pulmonary artery pressure; integral of the aortic flow velocity; myocardial performance index; rate of increase of left ventricular pressure; isovolumic relaxation time; E, A, Em, Am and Sm wave velocities; E wave deceleration time; E/A and E/Em ratios; and mitral regurgitation. Results: In the mean 24.18-month follow-up, 27 patients died. The mean ejection fraction was 26.6 ± 5.34%. In the multivariate analysis, the parameters ejection fraction (HR = 1.114; p = 0.3704), indexed left atrial volume (HR = 1.033; p < 0.0001) and E/Em ratio (HR = 0.95; p = 0.1261) were excluded. The indexed left atrial volume was an independent predictor in relation to the endpoint, and values > 70.71 mL/m2 were associated with a significant increase in mortality (log rank p < 0.0001). Conclusion: The indexed left atrial volume was the only independent predictor of mortality in this population of Chagasic patients with severe systolic dysfunction.
Palavras-chave: Echocardiography /diagnosis
Chagas disease
Survivorship (public health)
Chagas cardiomyopathy
País: Brasil
Unidade acadêmica: Faculdade de Medicina - FM (RG)
Citação: RASSI, Daniela do Carmo et al. Echocardiographic parameters and survival in chagas heart disease with severe systolic dysfunction. Arquivos Brasileiros de Cardiologia, Rio de Janeiro, v. 102, n. 3, p. 242-252, 2014.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.5935/abc.20140003
Identificador do documento: 10.5935/abc.20140003
URI: http://repositorio.bc.ufg.br/handle/ri/18367
Data de publicação: 2014
Aparece nas coleções:FM - Artigos publicados em periódicos

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