1-(4-Methoxyphenyl)-2-(6-methyl-2-nitro- 3-pyridyloxy)propan-1-one

Abstract

The title compound, C16H16N2O5, is a -ketoether derivative closely related to natural 8,40-oxyneolignans, which are of interest because of their moderate antifungal activity against systemic mycosis. The nitro group is not coplanar with the aromatic ring, as shown by a torsion angle of 47.2 (4) . The molecules are linked by two non-classical intermolecular CÐ H O hydrogen bonds with distances between donors and acceptors of 3.441 (5) and 3.539 (5) A Ê , leading to the formation of molecular stacking perpendicular to the bc plane.