Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/18557
Tipo do documento: Artigo
Título: Prevalence, genotype profile and risk factors for multiple human papillomavirus cervical infection in unimmunized female adolescents in Goiânia, Brazil: a community-based stud
Autor: Alves, Rosane Ribeiro Figueiredo
Turchi, Marília Dalva
Santos, Lyana Elias
Guimarães, Eleuse Machado de Britto
Garcia, Mônica Maria Danda
Seixas, Mirian Socorro Cardoso
Villa, Luisa Lina
Costa, Maria Cecilia Martins
Moreira, Marise Amaral Rebouças
Alves, Maria de Fátima Costa
Abstract: Background: The epidemiology of infection with multiple human papillomavirus (HPV) types in female adolescents is poorly understood. The purpose of this study was to explore the epidemiology of infection with multiple HPV types in adolescents and its association with demographic, behavioral and biological variables, as well as with cytological abnormalities. Methods: This community-based study included 432 sexually active females between 15 and 19 years of age. Genotyping for 30 HPV types was performed using a reverse blot strip assay/restriction fragment length polymorphism. Unconditional multivariate logistic regression was performed to identify factors significantly associated with HPV infection. The association between HPV infection and cytological abnormalities was calculated using a prevalence ratio. Results: The most common HPV types detected were 16, 51, 31, 52 and 18. Of the 121 HPV-positive women, 54 (44.6%) were infected with multiple HPV types. Having more than one lifetime sexual partner was associated with infection with any HPV infection, single HPV infection, and infection with multiple HPV types. The presence of cytological abnormalities was associated with infection with multiple HPV types. Conclusions: Co-infecting HPV genotypes occur in a high proportion of sexually active adolescents. Socio-demographic or sexual behavior factors associated with single HPV infection were similar to those associated with multiple HPV types. The higher risk of cytological abnormalities conferred by infection with multiple HPV types suggests a potential role of co-infection in the natural history of HPV infection.
Palavras-chave: Cytological abnormalities
Epidemiology
Multiple HPV infection
PCR-PGMY09/11/line blot hybridization/RFLP
Adolescents
Female
País: Estados unidos
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: ALVES,Rosane Ribeiro Figueiredo; TURCHI, Marília Dalva; SANTOS, Lyana Elias; GUIMARÃES, Eleuse Machado de Britto; GARCIA, Mônica Maria Danda; SEIXAS, Mirian Socorro Cardoso; VILLA, Luisa Lina; COSTA, Maria Cecília; MOREIRA, Marise Amaral Rebouças; ALVES, Maria de Fátima da Costa Alves. Prevalence, genotype profile and risk factors for multiple human papillomavirus cervical infection in unimmunized female adolescents in Goiânia, Brazil: a community-based study. BMC Public Health, New York, v. 13, n. 1041, 2013.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1186/1471-2458-13-1041
Identificador do documento: 10.1186/1471-2458-13-1041
URI: http://repositorio.bc.ufg.br/handle/ri/18557
Data de publicação: 2013
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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