Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/18858
Tipo do documento: Artigo
Título: Risk of coronary heart disease among HIV-infected patients: a multicenter study in Brazil
Autor: Fuchs, Sandra Cristina Pereira Costa
Alencastro, Paulo Ricardo de
Ikeda, Maria Letícia Rodrigues
Barcellos, Nêmora Tregnago
Wolff, Fernando Herz
Brandão, Ajácio Bandeira de Mello
Ximenes, Ricardo Arraes de Alencar
Miranda-Filho, Demócrito de Barros
Melo, Heloísa Ramos Lacerda de
Albuquerque, Maria de Fátima Pessoa Militão de
Montarroyos, Ulisses Ramos
Nery, Max Weyler
Marília Dalva, Turchi
Abstract: Cardiovascular disease has emerged as a crescent problem among HIV-infected population. This study aimed to determine the 10-year risk of coronary heart disease using the Framingham risk score among HIV-infected patients from three regions of Brazil. This is a pooled analysis of three cohort studies, which enrolled 3,829 individuals, 59% were men, 66% had white skin color, and mean age 39.0 ± 9.9 years. Comparisons among regions showed that thereweremarked differences in demographic, socioeconomic, clinical, and HIV-related characteristics. Prevalence of Framingham score ≥10 was 4.5% in the Southern, 4.2% in the Midwest, and 3.9% in the Northeast of Brazil.The Framingham score ≥10 was similar between regions for males, patients aged ≥60 years, with obesity, central obesity, hypertension, and diabetes mellitus. Women were three times more likely to have coronary heart disease in 10 years than men. Hypertension and diabetes increased more than four times the risk of coronary heart disease, followed by central obesity, obesity, and prehypertension.The use of antiretroviral agents and time since HIV diagnosis were not risk factors for coronary artery disease in 10 years. In conclusion, hypertension and diabetes are the strongest independent predictors of 10-year risk of coronary heart disease among HIV-infected population.
País: Gra-bretanha
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: FUCHS, Sandra C.; ALENCASTRO, Paulo R.; IKEDA, Maria Letícia R.; BARCELLOS, Nêmora T.; WOLFF, Fernando H.; BRANDÃO, Ajácio B. M.; XIMENES, Ricardo A. A.; MIRANDA-FILHO, Demócrito de B.; LACERDA, Heloísa Ramos; ALBUQUERQUE, Maria de Fátima P.M. de; MONTARROYOS, Ulisses Ramos; NERY, MaxW.; TURCHI, Marilia D. Risk of coronary heart disease among HIV-infected patients: a multicenter study in Brazil. The Scientific World Journal, London, v. 2013, e-163418, 2013.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1155/2013/163418
Identificador do documento: 10.1155/2013/163418
URI: http://repositorio.bc.ufg.br/handle/ri/18858
Data de publicação: 2013
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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