Use este identificador para citar ou linkar para este item: http://repositorio.bc.ufg.br/handle/ri/18967
Tipo do documento: Artigo
Título: Prevalence of hepatitis C virus infection and associated factors among male illicit drug users in Cuiabá, Mato Grosso, Brazil
Autor: Novais, Antônia Carlos Magalhães
Lopes, Carmen Luci Rodrigues
Reis, Nádia Rúbia da Silva
Martins, Regina Maria Bringel
Souto, Francisco José Dutra
Silva, Ágabo Macêdo Costa e
Abstract: Intravenous drug injection has been reported as the main risk factor for hepatitis C virus (HCV) infection. The aim of the present study was to describe the prevalence and the epidemiological profile of HCV infection among abusers of illegal injected and non-injected drugs in Cuiabá, state of Mato Grosso, Central Brazil. A cross-sectional study including 314 male drug users from eight detoxification centres was performed. Out of 314 subjects studied, 48 (15.2%) were intravenous drug users. Participants were interviewed and had blood samples taken and tested for the presence of anti-HCV antibodies. Positive samples were tested for the presence of HCV RNA. Genotyping was performed on HCV RNA-positive samples. The overall prevalence of anti-HCV antibodies was 6.4% (n = 20). Out of 20 anti-HCV antibody-positive subjects, 16 (80%) were also HCV RNA-positive. Genotype 1 predominated (75%), followed by 3a (25%). Subtype 1a was more common than 1b. HCV infection was more prevalent among intravenous drug users (33%) than non-injecting users (1.5%). Logistic regression analyses showed independent associations between HCV infection and intravenous drug use, imprisonment and increasing age. In the present study, inject- , imprisonment and increasing age. In the present study, injecting drug use was the factor most strongly associated to HCV infection and inhaling or sniffing did not represent an increased susceptibility to infection.
Palavras-chave: Epidemiology
Hepatitis C virus
Illicit drug users
HCV prevalence
HCV epidemiology
País: Brasil
Unidade acadêmica: Instituto de Patologia Tropical e Saúde Pública - IPTSP (RG)
Citação: NOVAIS, Antônia Carlos Magalhães et al. Prevalence of hepatitis C virus infection and associated factors among male illicit drug users in Cuiabá, Mato Grosso, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 104, n. 6, p. 892-896, Sept. 2009.
Tipo de acesso: Acesso Aberto
Identificador do documento: 10.1590/S0074-02762009000600012
Endereço da licença: An error occurred getting the license - uri.
An error occurred getting the license - uri.
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Identificador do documento: 10.1590/S0074-02762009000600012
URI: http://repositorio.bc.ufg.br/handle/ri/18967
Data de publicação: Set-2009
Aparece nas coleções:IPTSP - Artigos publicados em periódicos

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