25I-NBOH: a new potent serotonin 5-HT2A receptor agonist identified in blotter paper seizures in Brazil
Nenhuma Miniatura disponível
Data
2017-02-16
Título da Revista
ISSN da Revista
Título de Volume
Editor
Resumo
A new potent serotonin 5-HT2A receptor agonist
was identified in blotter papers by several state level
forensic laboratories in Brazil. The 25I-NBOH is a labile
molecule, which fragments into 2C-I when analyzed by
routine seized material screening gas chromatography
(GC) methods. GC–mass spectrometry (MS), liquid chromatography–quadrupole time-of-flight-MS, and Fourier
transform infrared and nuclear magnetic resonance analyses were performed to complete molecular characterization. Individual doses range from 300 to 1000 lg. Despite
its being a potent 5-HT2A receptor agonist, 25I-NBOH is
neither registered in the United Nations Office on Drugs
and Crime (UNODC) nor classified as a scheduled substance in most countries. Sweden and Brazil seem to be the
only countries to control 25I-NBOH. To our knowledge,
this is the first scientific report dealing with identification
of 25I-NBOH in actual seizures.
Descrição
Palavras-chave
25I-NBOH, NBOH, Phenethylamine derivatives, NPS, 5-HT2A receptor agonist
Citação
ARANTES, Luciano Chaves et al. 25I-NBOH: a new potent serotonin 5-HT2A receptor agonist identified in blotter paper seizures in Brazil. Forensic Toxicology, Tokyo, v. 35, p. 408-414, 2017. DOI: 10.1007/s11419-017-0357-x. Disponível em: https://link.springer.com/article/10.1007/s11419-017-0357-x. Acesso em: 16 fev. 2024.