Reparação tecidual após implante intraperitoneal de telas de polipropileno de gramaturas diferentes e tela de polipropileno com filme de poliglecaprone para correção de defeito da parede abdominal em ratos
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Data
2011-12-09
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Universidade Federal de Goiás
Resumo
High density polypropylene meshes are frequently chosen for repairs
onto the abdominal wall. Such meshes, when implanted through intraperitoneal
via may lead to visceral adherence formation, and, in most severe cases, to
intestinal obstruction. Low density meshes are a promising innovation, for
studies indicate that the lower the weight and porosity of the mesh, the lower
the inflammatory response will be. Those meshes may come associated to
absorbable biomaterials, which, when in contact with visceral peritoneum will
inhibit adhesiolysis. This following study investigates if low density
polypropylene mesh, associated or not to poliglecaprone film, implanted by
intraperitoneal via will reduce adherence incidence, maintaining the same
traction resistance as the host tissue. Surgical-produced wall defects in female
Wistar rats were surgically corrected by intraperitoneal implanting of high
density polypropylene mesh (Group PPa, n=18), low density polypropylene
mesh (Group PPb, n= 18) and low density polypropylene mesh coated with
poliglecaprone film (Group PPG, n=18). The animals were evaluated at 30, 90
and 180 post-implant days. In all three groups the meshes employed were able
to repair the abdominal defect. Between groups PPa and PPb, low density
polypropylene mesh had the lowest index of visceral adherence. The mesh of
the group PPG did not induce visceral adherence. At 180 days post implant,
type I collagen was the predominant element found, involving the mesh s
monofilaments, in all three groups. There was no significant difference among
groups PPa, PPb and PPG as to resistance and traction of the abdominal wall
at the end of the post implant 180 days.
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Palavras-chave
aderências , colágeno , ruptura , telas cirúrgicas , adherences , collagen , rupture , surgical meshes
Citação
SILVA, Luciano Schneider da. Tissue reparation after intraperitoneal implantation of polypropylene mesh different density and polypropylene mesh film coated with poliglecaprone for correctness of the abdominal wall defect in rats. 2011. 82 f. Tese (Doutorado em Ciências Agrárias) - Universidade Federal de Goiás, Goiânia, 2011.