Avaliação histopatológica, histoquímica e morfométrica dos efeitos da toxicidade aguda do herbicida roundup® nas brânquias e no fígado do peixe Poecilia vivipara
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Data
2009-05-20
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Universidade Federal de Goiás
Resumo
The indiscriminate use of agricultural pesticides, which contaminate the soil, water, and
human beings, has become a problem that causes great concern nowadays. We studied
the acute toxic effect of the herbicide Roundup® on animal behavior, tissue, and cells of
the neotropical fish species Poecilia vivipara gills and liver in order to determine and
compare their histoarchitecture, as well as to identify possible morphological
alterations. The average lethal concentrations of Roundup® were calculated and, after
that, the specimens were treated with acute exposure of this herbicide (24 h) at the
concentrations of 0, 15, 25, and 35 μl per liter of water. The gills and livers were
dissected, fixed in neuter formalin and Karnovsky s solution. The analyses, carried out
using basic histological, classical histochemical, and morphometric tests, allowed the
identification of alterations in the specimens treated compared to the control group. The
alterations in animal behavior, tissue, and cells evidenced in this study confirmed the
toxic effect of Roundup® on the model-test. Consequently, it is advisable to find a
balance between the benefits of this type of product and the protection of the
environment and human health.
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FARIA, Joana Cristina Neves de Menezes. Histopathological evaluation, immunohistochemistry and morphometric analysis of the effects of acute toxicity of the herbicide Roundup ® in gills and liver of the fish Poecilia vivipara. 2009. 56 f. Dissertação (Mestrado em Ciências Biolóicas) - Universidade Federal de Goiás, Goiânia, 2009.