Micro-organismos envolvidos em infecções urinárias de mulheres com idade superior a 15 anos atendidas no HC-UFG em 2009 e os perfis de suscetibilidade aos antimicrobianos
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Data
2011-05-06
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Universidade Federal de Goiás
Resumo
A urinary tract infection (UTI) is a very common disease and can occur at any age. The
vast majority of UTIs is caused by enteric bacteria. The study aimed to identify the
etiologic agents most frequently, the profile of antibiotic susceptibility and the factors
possibly associated to the UTIs recurrents in women older than 15 years, cared for and
/ or admitted to the Hospital of the University of Goias. From March to November
2009, were invited and accepted to participate in the study 923 women in this age group
and they were interviewed using a questionnaire about demographics data and risk
factors for recurrent infections. Escherichia coli was the most frequent agent accounting
for 67.9% of the total, followed by Enterobacter sp (6.2%), Klebsiella sp (6.2%),
Proteus mirabilis (4.5%), Morganella morganii (4.0 %), Acinetobacter baumannii
(2.8%) and Staphylococcus aureus (2.2%). %). E. coli showed higher rates of resistance
to ampicillin in 46.7% patients with recurrent infection and 50.0% in infections nonrecurring;
amoxicillin/clavulanate (32.6% and 35.7%), trimethoprim-sulfamethoxazole
(30,0 and 25,0%, respectively) and 100,0% susceptibility to imipenem and
nitrofurantoin in both groups. Enterobacter sp showed greater resistance to ampicillin,
amoxicillin/clavulanic, norfloxacin and gentamicin (>88.0%) and greater susceptibility
to amikacin, cefepime, imipinem and cephalosporins. Klebsiella sp showed high
resistance to ampicillin and amoxicillin / clavulanate (> 60.0%) and greater
susceptibility to quinolones (> 60.0%), amikacin and imipenem (100.0%) in both
groups. There were no statistically significant differences between the risk for recurrent
infection or not assessed for menopause, hypertension, hysterectomy, SEL (Systemic
Erythematosus Lupus) and smoking. The only risk factor associated to recurrent
infection in patients older than 50 years with diabetes. In this study, there was a greater
number of E. coli in UTIs, followed by other enterobacteria such as Enterobacter sp
and Klebsiella sp. Among all drugs tested, all the micro-organisms, were resistant
generally to penicillins, being the most effective quinolones and carbapenems.
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SANTOS SOBRINHO, Rosemary Alves dos. Micro-organisms involved in urinary tract infections in women aged over 15 years in HC-UFG attended in 2009 and profiles for antimicrobial susceptibility. 2011. 68 f. Dissertação (Mestrado em Ciências da Saúde - Medicina) - Universidade Federal de Goiás, Goiânia, 2011.