Efeitos clínicos, laboratoriais e ecocardiográficos da estimulação cardíaca convencional em pacientes submetidos a implante de marca-passo com função ventricular normal
Carregando...
Data
2013-02-22
Autores
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade Federal de Goiás
Resumo
Introduction: Right ventricular pacing can be deleterious in patients with left ventricular dysfunction, but in patients with normal function the impact of this stimulation and triggering ventricular dyssynchrony clinically relevant is not fully established. Objectives: To evaluate clinical findings of patients with previously normal ventricular function, who underwent implantation of a pacemaker. Methods: We studied prospectively 20 patients (60% male and the average age was 58 years) underwent implantation of a pacemaker with the following inclusion criteria: normal ventricular function defined by echocardiography and the presence of ventricular pacing 90% higher (generator telemetry). We evaluated the following parameters: Class functional (New York Heart Association) 6-minute walk test, dosage of B-type natriuretic peptide (BNP), and conventional echocardiographic and evaluation dyssynchrony and intraventricular (by tissue Doppler, M-mode and pulsed Doppler) and the quality of life assessment by SF-36 Health Survey. The evaluation was done at 10 days (t1), 4 months (t2), 8 months (t3), 12 months (t4) and 24 months (t5). Data were compared over time according to ANOVA repeated measures (rmANOVA). Results: Of the following evaluated data showed no statistically significant variation (p> 0.05): conventional echocardiographic parameters, interventricular and intraventricular dyssynchrony. The six minute walk test, functional class and BNP worsened at the end of two years (p <0.05). Evaluation showed initial improvement in QOL domains: physical functioning, social and general health and worsens at the end of the two years. Conclusion: After 24 months the right ventricular pacing, in patients with normal function, correlated with worsening of ventricular function assessed clinically (class functional walk test and QOL) and measure laboratory (BNP).
Descrição
Palavras-chave
Citação
Sá, Luiz Antônio Batista de - Efeitos clínicos, laboratoriais e ecocardiográficos da estimulação cardíaca convencional em pacientes submetidos a implante de marca-passo com função ventricular normal - 2013 - 114 f. - Tese - Programa de Pós-graduação em Ciências da Saúde (FM) - Universidade Federal de Goiás - Goiânia -Goiás -Brasil.