Prevalência e fatores associados à soropositividade pelo Toxoplasma gondii em mulheres atendidas no Programa de Proteção à Gestante em Goiânia, GO
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2009-12-11
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Universidade Federal de Goiás
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The acute toxoplasmosis during pregnancy is an infection that can be transmitted to the fetus, causing a disease that varies in severity depending on the time of pregnancy when fetal infection occurred. Can be severe and cause miscarriage or major sequelae (neuro-optical) in survivors. The detection of women's vulnerability to infection and early diagnosis of acute infection in pregnant women provide for the use of prophylactic measures to prevent maternal infection and/or introducing therapeutic measures that can reduce the severity of fetal disease. Although toxoplasmosis screening is not mandatory in Brazil, in the State of Goiás, through the Pregnancy Protection Program, several infections are identified during prenatal care such as toxoplasmosis. This study aimed at estimating the prevalence of anti-Toxoplasma gondii antibodies and analyzing factors associated to seropositivity in pregnant women assisted by the Pregnancy Protection Program. This is a cross-sectional study from the Pregnancy Protection Program database records which considered the serologic trials outcomes carried out in filter paper samples for the IgG and IgM markers in pregnant women living in Goiânia screened in 2008. In order to amplify and improve the quality of data analysis, was carried out a deterministic linkage technique with Live Birth Information System database, thus linked to 10,316 records out of 12,843 records which were analyzed (80.3%). The infection prevalence was of 68.3% (CI 95%: 67.5-69.1), 0.74% (95/12,846) of which presented IgG and IgM reagents. The serum IgM and IgG avidity confirmation test was carried out in 93.7% (89/95) pregnant women suggestive of acute infection. The gestational week of the new collection was identified in 82 of them, and 52.5% (43/82) of which were on the 16th week of gestation or more weeks, it is not possible to determine if the infection occurred during pregnancy, and among these ones, the IgG avidity test value was higher than 60% in 35/43 pregnant women. The statistically associated variables (p<0,05) seropositivity were age group equal or higher than 20 years, black and mixed-race, school completion rate lower than 12 years and multiple pregnancies. The outcomes show a high prevalence of infection among pregnant women living in Goiânia and high patient compliance with the Program to perform the confirmatory test, however, the Pregnancy Protection Program s database presented a high percentage of records with variable not satisfied, justifying the adoption of strategies aimed at health professionals about the importance of filling the pregnancy's card and the information to the surveillance systems of State.
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SARTORI, Ana Lucia. The Prevalence and factors associated with seropositivity to Toxoplasma gondii in women assisted by the Pregnancy Protection Program in Goiânia, GO. 2009. 92 f. Dissertação (Mestrado em Cuidado em Enfermagem) - Universidade Federal de Goiás, Goiânia, 2009.