Contribuição ao estudo de reações mediadas por calcogenetos Zn e Cu: hidrocalcogenação de ácidos e ésteres e síntese de sulfetos arílicos
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Data
2012-05-04
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Universidade Federal de Goiás
Resumo
This work describes some studies on the preparation of unsymmetrical
diaryl thioethers catalyzed by Copper(I)-Senelenophene-2-carboxylate. The
results concern to the catalyzed cross-coupling reaction between aryl halides
and aryl or alkylthiols using Copper(I)-Senelenophene-2-carboxylate (CuSC) a
new Cu-catalyzed one-pot protocol. The products were obtained in good to
excellent yields under relatively mild reaction conditions presenting
chemoselectivity and functional group tolerance. Additionally, we have developed a chemio-, regio and stereoselective
synthesis of vinyl chalcogenides compounds promoted by zinc chalcogenolates.
In this protocol the reductive cleavage of chalcogen bond by the Zn/NH4OH
system led to zinc chalcogenolates. The reaction was carried out with acids and
esters propiolics afford β-chalcogenacrillic acids and esters under mild and
basic conditions. The stereochemistry corresponding to anti-Markovnikov
addition of the chalcogenolate constituents across the triple bond were obtained
in good yields.
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Nunes, Vanessa Loren. Contribuição ao estudo de reações mediadas por calcogenetos Zn e Cu: hidrocalcogenação de ácidos e ésteres e síntese de sulfetos arílicos. 2012. 117 f. Dissertação (Mestrado em Química) - Universidade Federal de Goiás, Goiânia, 2012.