Sarcopenia em idosos: revisão, prevalência, concordância entre métodos diagnósticos e antropometria como proposta de rasatreamento
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2013-06-21
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Universidade Federal de Goiás
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The aim of this study was to review methods and diagnostic criteria for
sarcopenia available in the literature to estimate the prevalence and
concordance between them, in a sample of elderly Goiânia, and propose
anthropometry for screening sarcopenia. To review methods we used the
recommendations for systematic review and meta-analysis of the Preferred
Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA
Statement. For other purposes, we used a subsample of 132 elderly Senior
Project/ Goiânia, selected in proportion to the Sanitation Districts of Goiânia.
The data were collected by staff previously trained and standardized.
Sarcopenia was analyzed by mass and muscle strength. The mass mucular
was estimated by dual X-ray absorptiometry (DEXA), bioelectrical impedance
analysis (BIA) and anthropometry, and muscle strength through hand grip
strength (FPP). Analyses were performed in STATA 12.0, comparison of
means and proportions, estimation of prevalence and prevalence ratio,
Kappa, calculation of sensitivity and specificity analysis and ROC (receiver
operator characteristic) curve. The project was approved by the Ethics
Committee of the Federal University of Goiás. In 28 prevalence studies
reviewed were found three methods for the diagnosis of sarcopenia: DEXA
BIA and anthropometry with significant variations in prevalence as sex and
the method adopted. Applying the diagnostic criteria found in the subsample
Elderly Project/ Goiânia, the prevalence of sarcopenia ranged from 60.6% to
8.3% for the criteria of muscle mass and 54.2% to 48.8% for the strength,
increasing in age and is more prevalent in men by criteria of muscle mass
and women by criteria muscle strength. There was good agreement between
two diagnostic criteria using DEXA, and moderate to weak for others.
Anthropometric measurements of the circumference of the calf (CP), midlearm
circumference (MAMC) and brachial circumference (CB) have been
proposed for screenig sarcopenia and all showed good sensitivity and
specificity for the cutoff of DEXA, and the CP had the best performance. We
conclude that there are different methods and criteria for diagnosis of
sarcopenia and its aplicabillity both in elderly sample of Goiânia, as other
results in different prevalence rates by sex and age. The only good
agreement between the two methods indicates DEXA both the need for an
operational definition and the need for early detection. Anthropometric
measurements of CP, CMB and CB can be used for tracking and consequent
prevention of adverse events in elderly health resulting from sarcopenia
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PAGOTTO, Valéria. Sarcopenia em idosos: revisão, prevalência, concordância entre métodos diagnósticos e antropometria como proposta de rasatreamento. 2013. 193 f. Tese (Doutorado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2013.