Estudo comparativo entre o Bevacizumabe intravitreo e a fotocoagulação a laser com oftalmoscopio binocular indireto na retinopatia da prematuridade
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2010-07-06
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Universidade Federal de Goiás
Resumo
OBJECTIVES: To compare the response of bevacizumab and the
response of the laser photocoagulation with indirect binocular ophthalmoscope
(IBO) in infants with retinopathy of prematurity (ROP) stages II or III.
METHODS: Data collection was performed in the neonatal intensive care unit of
the Hospital Materno Infantil, from May to November 2009. Preterm infants with
ROP stages II or III, with or without the plus disease were included. They were
divided into two groups: on group I, an intra-vitreous injection of bevacizumab
was performed and on group II, laser photocoagulation with IBO was performed.
RESULTS: In group I, from the 20 eyes that underwent the application of
bevacizumab, there was total regression of ROP with one application in 14 eyes,
being 4 eyes with complete regression with two doses of bevacizumab, and 2
eyes with total regression after two applications of bevacizumab and one
application of laser. On group II, from the 20 eyes treated with laser
photocoagulation with IBO, there was total regression of ROP with laser therapy
in 14 eyes and there was total regression with two laser sessions in 6 eyes.
CONCLUSION: Bevacizumab is effective if compared to laser photocoagulation
in ROP stages II and III.
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MARQUEZ, Tatiana Vieira de Brito. Estudo comparativo entre o Bevacizumabe intravitreo e a fotocoagulação a laser com oftalmoscopio binocular indireto na retinopatia da prematuridade. 2010. 110 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2010.