Epidemiologia da sífilis em usuários de crack institucionalizados em Goiânia, Goiás
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2016-04-26
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Universidade Federal de Goiás
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Crack users are at high risk for syphilis, due to multiple risk behaviors, such as inconsistent
condom use, exchanging sex for money and/or drugs and multiple sexual partners. The aim
of this study was to investigate the epidemiology of syphilis in institutionalized crack users in
Goiânia, Goiás. Between 2012 and 2013, a cross-sectional study was conducted with 600 users
of a reference unit for chemical dependency treatment of Goiás. All participants were
interviewed regarding socio-demographic characteristics and risk factors for syphilis. Blood
samples were then collected for the detection of anti-Treponema pallidum antibodies using
enzyme-linked immunosorbent assay (ELISA). Positive samples were retested by the Venereal
Disease Research Laboratory (VDRL). Active syphilis was considered when there was a positive
ELISA result and VDRL titers ≥ 1:8. Of the 600 samples tested by ELISA, 13.8% (95% CI:
11.3 to 16.8%) were positive and 4.5% (95% CI: 3.1 to 6.5%) had titles VDRL ≥ 1:8. The
prevalence of exposure to Treponema pallidum and active syphilis was three times greater in
women than in men (p < .001). In multiple regression analysis, female sex (adjusted
prevalence ratio [APR]: 3.73; p < .001), exchange sex for money and/or drugs (APR: 3.22; p
= .040) and a history of genital ulcers (APR: 4.12; p = .010) were associated with active
syphilis. Furthermore, it was observed that the prevalence of infection decreased by 12% for
each year of formal study (APR: 0.88; p = .030). The results of this research show high
prevalence of syphilis in the investigated crack users and indicate the need to implement
strategies for prevention and control of this infection in these individuals, including health
education activities, diagnosis of infection in clinical treatment for chemical dependency and
treatment of positive cases.
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GUIMARÃES, R. A. Epidemiologia da sífilis em usuários de crack institucionalizados em Goiânia, Goiás. 2016. 118 f. Dissertação (Mestrado em Enfermagem) - Universidade Federal de Goiás, Goiânia, 2016.