Avaliação dos indicadores de qualidade dos exames citopatológicos realizados no centro de análises clínicas Rômulo Rocha da Universidade Federal de Goiás
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2016-04-06
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Universidade Federal de Goiás
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Introduction: cervical cancer is the third cause of women’s death by cancer in the
world and its incidence is linked to high-risk oncogenic human papillomavirus (HPV).
The cytodiagnosis and tracking of the disease are made by the Papanicolaou technique.
Quality control programs have been implemented in order to correct errors of diagnosis,
particularly with regard to false-negative results. Objective: to evaluate the internal
quality control indicators and quality management program in the section of
cytopathology of a university laboratory in the years 2007-2014. Methods: All results
of cervical smears tests (taken from the SISCAN – Sistema de Informação do Câncer –
The Cancer Information System) of women aged ≥15 years at the time of Pap smear
specimen collection during January 2007 to December 2014. The final results of the
cytopathology examinations were classified in accordance with the Bethesda System.
The variables included in the database were woman’s name, date of birth, and age at
time of collection (15–30, 31–40 and >40 years). Results: In this period 50,286 tests
were carried out, 44,386 (91.34%) being negative for malignancy and 4,209 (8.66%)
abnormal. The positivity rate was 8.69%; the percentage of tests consistent with ASC
(Atypical Squamous Cells), between satisfactory exams was 4.12%; the percentage of
tests compatible with ASC among abnormal tests was 47.87%; the ASC/SIL (Squamous
Intraepithelial Lesion) ratio was 0.97 and the percentage of HSIL (High Grade
intraepithelial Lesion squamous high degree) between satisfactory tests was 2.21%, and
false-negative results in 5-years retrospective review was 4.97%. Conclusion: The rates
obtained were uniforms over the years and within the recommended values. This
demonstrates the efficiency and linearity of the internal quality control, reflected in the
commitment of the team involved in, through continuing education, whose goal is to
detect and correct false-negative results.
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CARDOSO FILHO, L. I. Avaliação dos indicadores de qualidade dos exames citopatológicos realizados no centro de análises clínicas Rômulo Rocha da Universidade Federal de Goiás. 2016. 61 f Dissertação (Mestrado em Medicina Tropical e Saúde Publica) - Universidade Federal de Goiás, Goiânia, 2016.