Correlação da resistência à insulina, circunferência da cintura, e índice de massa corporal com a pressão arterial de adolescentes
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2015-09-25
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Universidade Federal de Goiás
Resumo
Introduction: Among the major risk factors for cardiovascular diseases are
high blood pressure (hypertension), obesity and insulin resistance (IR).
Studies show that blood pressure (BP) increases progressively with an
increase of the body mass index (BMI) and in individuals with increased waist
circumference (WC), they have a higher risk of developing hypertension, IR
and other metabolic disorders since childhood. Objective: To evaluate the
correlation between RI, WC and BMI in adolescents with altered levels of
PA. Methods: Cross-sectional study with a representative sample of 1025
adolescents aged 12 to 17 years enrolled in public and private schools in a
large city. Two groups were evaluated, one formed by the PA that had
changed the assessment by casual measurement and / or Home Blood
Pressure Measurement (HBPM) and another group formed by those with
normal BP. Evaluated anthropometric indicators for BMI and WC calculation.
Classified as abnormal blood pressure those with BP percentile> 90 on
casual measurement and / or HBPM. Measured fasting plasma glucose and
plasma insulin using the HOMA-IR index as indicative of RI. Results: We
studied 162 adolescents (35 normal BP group and 127 of the amended BP
group) and 61.1% (n = 99) boys, mean age 14.9 ± 1.62 years. Observed 38
children (23.5%) with abnormal HOMA-IR index. Teenagers with altered BP
had significantly higher mean values of WC, BMI and HOMA-IR (p <0.05).
The WC was higher in boys in both groups (p <0.05), and only changed the
BP group was observed HOMA-IR values higher among girls (p <0.05). The
correlation between BMI and HOMA-IR in altered pressure group, was
moderate and significant (ρ = 0.394; p <0.001), higher than that found in the
normal pressure group. The correlation between WC and HOMA-IR was also
significant and moderate and similar in both groups (ρ = 0.345; p = <0.05). In
HOMA-IR logistic regression analysis was predictor of change in BP (OR =
2.0 / p = 0.001).Conclusion: There is a significant association between RI
and PA with impact since childhood. The correlation and association between
cardiovascular risks markers observed stronger in the amended BP group
suggests that primary prevention measures such risk factors should be
implemented early.
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MORAIS, P. R. S. Correlação da resistência à insulina, circunferência da cintura, e índice de massa corporal com a pressão arterial de adolescentes. 2015. 60 f. Dissertação (Mestrado em Ciências da Saúde) - Universidade Federal de Goiás, Goiânia, 2015.